Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1021

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,141,842	-		Rv1020	0.78	-0.3
1,141,856	+		Rv1020	0.78	+0.3
1,141,857	-		Rv1020	0.78	-0.4
1,141,857	-		Rv1020	0.78	-0.4
1,141,960	-		Rv1020	0.81	-0.1
1,142,033	+		Rv1020	0.83	-0.9
1,142,033	+		Rv1020	0.83	-0.0
1,142,034	-		Rv1020	0.83	-0.1
1,142,034	-		Rv1020	0.83	-0.2
1,142,067	-		Rv1020	0.84	+0.4
1,142,079	-		Rv1020	0.84	-0.8
1,142,174	+		Rv1020	0.87	+0.2
1,142,265	+		Rv1020	0.89	+1.0
1,142,266	-		Rv1020	0.89	+0.3
1,142,276	+		Rv1020	0.89	-0.5
1,142,277	-		Rv1020	0.89	-0.4
1,142,441	+				+0.1
1,142,456	+				-0.1
1,142,457	-				-0.3
1,142,600	-				+0.2
1,142,602	-				+1.0
1,142,602	-				+0.1
1,142,602	-				+0.6
1,142,602	-				-0.1
1,142,653	+				+0.9
1,142,654	-				-0.2
1,142,752	+				+0.6
1,142,869	-		Rv1021	0.20	+0.1
1,143,032	-		Rv1021	0.37	+1.2
1,143,711	+				+0.8
1,143,713	+				+1.0
1,143,973	+		Rv1022	0.32	-0.3
1,144,109	+		Rv1022	0.51	+0.0
1,144,110	-		Rv1022	0.51	-1.3
1,144,331	-		Rv1022	0.81	-0.0
1,144,334	+		Rv1022	0.82	+2.0
1,144,334	+		Rv1022	0.82	-0.9
1,144,407	+				-0.5
1,144,411	+				+0.1
1,144,466	-				+1.1
1,144,466	-				+0.4