Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1019

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,138,211	+				-0.5
1,138,212	-				-0.3
1,138,424	+		Rv1019	0.18	-0.6
1,138,424	+		Rv1019	0.18	-0.9
1,138,425	-		Rv1019	0.19	-0.2
1,138,441	+		Rv1019	0.21	-0.5
1,138,441	+		Rv1019	0.21	-0.6
1,138,471	+		Rv1019	0.26	-0.1
1,138,585	+		Rv1019	0.45	-0.2
1,138,585	+		Rv1019	0.45	-1.6
1,138,586	-		Rv1019	0.46	-1.1
1,138,586	-		Rv1019	0.46	-1.0
1,138,753	+		Rv1019	0.74	-1.1
1,138,753	+		Rv1019	0.74	-1.2
1,138,754	-		Rv1019	0.74	-0.7
1,138,895	+				-2.0
1,138,953	-				-0.2
1,138,953	-				+0.5
1,138,953	-				+0.1
1,139,362	-		Rv1020	0.11	-0.0
1,139,492	+		Rv1020	0.14	+2.0
1,139,492	+		Rv1020	0.14	-0.6
1,139,492	+		Rv1020	0.14	-1.1
1,139,493	-		Rv1020	0.14	+0.4
1,139,495	-		Rv1020	0.14	-0.0
1,139,507	-		Rv1020	0.15	-0.7
1,139,507	-		Rv1020	0.15	-0.0