Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0991c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,107,224	-		Rv0989c	0.84	-0.1
1,107,271	+		Rv0989c	0.89	-0.8
1,107,394	+				-0.1
1,107,421	+				-1.1
1,107,433	+				-0.6
1,107,433	+				+0.1
1,107,433	+				-0.1
1,107,433	+				-0.2
1,107,434	-				-0.8
1,107,434	-				-1.3
1,107,489	-				+2.7
1,107,493	+				-3.0
1,107,493	+				+0.8
1,107,494	-				-0.0
1,107,494	-				-0.0
1,107,538	+		Rv0990c	0.14	-0.8
1,108,348	-		Rv0991c	0.53	+0.7
1,108,488	+				-0.6
1,108,488	+				+0.4
1,108,495	-				-0.1
1,108,495	-				-0.4
1,108,638	+		Rv0992c	0.10	-0.5
1,108,638	+		Rv0992c	0.10	+0.1
1,108,639	-		Rv0992c	0.10	+2.0
1,108,639	-		Rv0992c	0.10	+0.2
1,108,639	-		Rv0992c	0.10	-0.1
1,108,699	-		Rv0992c	0.20	-0.4
1,108,738	+		Rv0992c	0.27	-1.0
1,108,738	+		Rv0992c	0.27	-0.1
1,108,739	-		Rv0992c	0.27	+0.1
1,108,894	+		Rv0992c	0.53	+0.2
1,108,895	-		Rv0992c	0.53	-0.5
1,109,027	-		Rv0992c	0.76	-2.6
1,109,027	-		Rv0992c	0.76	-0.1
1,109,288	+				-0.1
1,109,291	+				+0.5
1,109,291	+				-0.0
1,109,291	+				+0.5