Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0893c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0892 and Rv0893c overlap by 23 nucleotidesRv0893c and Rv0894 are separated by 228 nucleotides Rv0892: Rv0892 - Probable monooxygenase, at 993,853 to 995,340 Rv0892 Rv0893c: Rv0893c - Possible S-adenosylmethionine-dependent methyltransferase, at 995,318 to 996,295 Rv0893c Rv0894: Rv0894 - Possible transcriptional regulatory protein (possibly LuxR-family), at 996,524 to 997,705 Rv0894 Position (kb) 995 996 997Strain fitness (log2 ratio) -1 0 1at 994.479 kb on + strand, within Rv0892at 994.547 kb on - strand, within Rv0892at 994.548 kb on + strand, within Rv0892at 994.555 kb on + strand, within Rv0892at 994.558 kb on - strand, within Rv0892at 995.198 kb on - strandat 995.271 kb on - strandat 995.319 kb on + strandat 995.345 kb on + strandat 995.388 kb on - strandat 995.420 kb on - strand, within Rv0893cat 995.867 kb on + strand, within Rv0893cat 996.105 kb on + strand, within Rv0893cat 996.510 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL
remove
994,479 + Rv0892 0.42 -1.6
994,547 - Rv0892 0.47 +1.0
994,548 + Rv0892 0.47 +1.4
994,555 + Rv0892 0.47 -1.0
994,558 - Rv0892 0.47 -0.9
995,198 - +0.0
995,271 - +0.1
995,319 + -0.3
995,345 + -1.4
995,388 - -0.2
995,420 - Rv0893c 0.10 +0.7
995,867 + Rv0893c 0.56 +0.6
996,105 + Rv0893c 0.80 +0.0
996,510 + -0.1

Or see this region's nucleotide sequence