Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0887c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0886 and Rv0887c overlap by 18 nucleotides Rv0886: Rv0886 - Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase), at 983,803 to 985,530 Rv0886 Rv0887c: Rv0887c - Conserved hypothetical protein, at 985,513 to 985,971 Rv0887c Position (kb) 985 986Strain fitness (log2 ratio) -1 0 1at 985.157 kb on - strand, within Rv0886at 985.218 kb on + strand, within Rv0886at 985.219 kb on - strand, within Rv0886at 985.219 kb on - strand, within Rv0886at 985.810 kb on - strand, within Rv0887cat 985.899 kb on - strand, within Rv0887cat 986.901 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL
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985,157 - Rv0886 0.78 +0.2
985,218 + Rv0886 0.82 -1.3
985,219 - Rv0886 0.82 -0.5
985,219 - Rv0886 0.82 -0.3
985,810 - Rv0887c 0.65 +0.9
985,899 - Rv0887c 0.84 -0.1
986,901 + +0.4

Or see this region's nucleotide sequence