Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0874c and Rv0875c are separated by 99 nucleotides Rv0875c and Rv0876c overlap by 4 nucleotides Rv0876c and Rv0877 are separated by 137 nucleotides Rv0877 and Rv0878c are separated by 8 nucleotides
Rv0874c: Rv0874c - Conserved hypothetical protein, at 972,546 to 973,706
Rv0874c
Rv0875c: Rv0875c - Possible conserved exported protein, at 973,806 to 974,294
Rv0875c
Rv0876c: Rv0876c - Possible conserved transmembrane protein, at 974,291 to 975,937
Rv0876c
Rv0877: Rv0877 - Conserved hypothetical protein, at 976,075 to 976,863
Rv0877
Rv0878c: Rv0878c - PPE family protein PPE13, at 976,872 to 978,203
Rv0878c
Position (kb) 974
975
976 Strain fitness (log2 ratio) -2
-1
0
1
2 at 974.464 kb on - strand, within Rv0876c at 974.464 kb on - strand, within Rv0876c at 974.851 kb on - strand, within Rv0876c at 975.746 kb on - strand, within Rv0876c at 975.850 kb on - strand at 975.850 kb on - strand at 975.850 kb on - strand at 975.850 kb on - strand at 975.850 kb on - strand at 975.871 kb on - strand at 975.871 kb on - strand at 975.871 kb on - strand at 976.045 kb on - strand at 976.045 kb on - strand at 976.058 kb on + strand at 976.214 kb on - strand, within Rv0877 at 976.315 kb on + strand, within Rv0877 at 976.316 kb on - strand, within Rv0877 at 976.369 kb on - strand, within Rv0877 at 976.369 kb on - strand, within Rv0877 at 976.603 kb on + strand, within Rv0877 at 976.603 kb on + strand, within Rv0877 at 976.603 kb on + strand, within Rv0877 at 976.604 kb on - strand, within Rv0877 at 976.621 kb on - strand, within Rv0877 at 976.621 kb on - strand, within Rv0877 at 976.621 kb on - strand, within Rv0877 at 976.621 kb on - strand, within Rv0877 at 976.621 kb on - strand, within Rv0877 at 976.703 kb on + strand, within Rv0877 at 976.703 kb on + strand, within Rv0877 at 976.704 kb on - strand, within Rv0877 at 976.704 kb on - strand, within Rv0877 at 976.704 kb on - strand, within Rv0877 at 976.704 kb on - strand, within Rv0877 at 976.704 kb on - strand, within Rv0877 at 976.751 kb on - strand, within Rv0877 at 976.807 kb on + strand at 976.808 kb on - strand at 976.816 kb on + strand at 976.817 kb on - strand at 976.817 kb on - strand at 976.861 kb on + strand at 976.861 kb on + strand at 976.862 kb on - strand at 976.862 kb on - strand at 976.932 kb on + strand at 976.933 kb on - strand at 976.933 kb on - strand at 976.933 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 974,464 - Rv0876c 0.11 -1.8 974,464 - Rv0876c 0.11 -1.9 974,851 - Rv0876c 0.34 -1.9 975,746 - Rv0876c 0.88 -1.3 975,850 - -0.7 975,850 - -0.6 975,850 - -0.3 975,850 - -0.1 975,850 - -0.0 975,871 - -1.2 975,871 - -0.7 975,871 - -0.5 976,045 - +0.6 976,045 - +0.2 976,058 + +0.3 976,214 - Rv0877 0.18 -1.9 976,315 + Rv0877 0.30 -0.2 976,316 - Rv0877 0.31 -0.4 976,369 - Rv0877 0.37 -0.1 976,369 - Rv0877 0.37 +0.9 976,603 + Rv0877 0.67 +0.2 976,603 + Rv0877 0.67 -0.3 976,603 + Rv0877 0.67 -0.8 976,604 - Rv0877 0.67 -0.3 976,621 - Rv0877 0.69 -0.2 976,621 - Rv0877 0.69 -0.1 976,621 - Rv0877 0.69 -0.1 976,621 - Rv0877 0.69 +0.5 976,621 - Rv0877 0.69 +0.1 976,703 + Rv0877 0.80 -0.2 976,703 + Rv0877 0.80 +0.1 976,704 - Rv0877 0.80 +0.2 976,704 - Rv0877 0.80 +1.9 976,704 - Rv0877 0.80 +1.4 976,704 - Rv0877 0.80 +0.0 976,704 - Rv0877 0.80 -0.2 976,751 - Rv0877 0.86 -0.1 976,807 + -0.1 976,808 - -0.7 976,816 + -0.9 976,817 - -0.9 976,817 - -0.9 976,861 + +0.1 976,861 + -0.6 976,862 - +0.4 976,862 - +1.9 976,932 + -0.9 976,933 - -1.9 976,933 - -1.3 976,933 - -0.5
Or see this region's nucleotide sequence