Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0867c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
963,449	+		Rv0865	0.12	-0.4
963,554	-		Rv0865	0.34	+0.4
963,657	+		Rv0865	0.55	-0.0
963,657	+		Rv0865	0.55	-0.2
963,793	+		Rv0865	0.83	+1.0
963,793	+		Rv0865	0.83	-0.9
963,794	-		Rv0865	0.84	+0.2
963,794	-		Rv0865	0.84	+2.0
964,022	+		Rv0866	0.36	+0.4
964,022	+		Rv0866	0.36	+0.1
964,023	-		Rv0866	0.36	-0.5
964,074	+		Rv0866	0.48	-1.2
964,075	-		Rv0866	0.48	-0.3
964,325	+				+4.3
964,325	+				+1.2
964,325	+				-0.6
964,326	-				-0.3
964,326	-				-0.6
964,326	-				-1.3
964,326	-				-0.0
964,326	-				+0.4
964,326	-				-0.0
964,326	-				-0.2
964,326	-				-1.6
964,401	+				-1.2
964,402	-				-0.3
964,402	-				+0.2
964,403	+				+0.2
965,345	+		Rv0867c	0.84	+0.9
965,465	-				+0.1
965,517	+				+1.4
965,517	+				-0.4
965,518	-				-0.4
965,518	-				+0.4
965,535	+				-0.3
965,536	-				+0.5
965,536	-				-0.6
965,536	-				+0.4
965,536	-				-0.4
965,540	+				-0.4
965,544	+				-1.2
965,629	-				-0.9
965,629	-				+0.9
965,629	-				-1.6
965,668	-				+0.5
965,668	-				+0.7
965,845	+				-0.8
966,004	+				-1.8
966,005	-				+0.2
966,005	-				-0.9
966,005	-				-0.3
966,007	+				-0.2
966,007	+				-0.1
966,007	+				-2.0
966,074	+		Rv0868c	0.33	-0.7
966,074	+		Rv0868c	0.33	-0.1
966,212	+		Rv0868c	0.82	+0.1