Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0818

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
910,003	+				-0.4
910,003	+				-0.5
910,004	-				+0.4
910,004	-				+2.9
910,895	+				+0.0
910,901	+				+0.3
910,982	+				+0.5
910,982	+				-0.9
910,982	+				+0.6
910,982	+				+0.6
910,983	-				-1.2
910,983	-				+0.1
910,983	-				-2.7
910,985	+				+3.2
910,985	+				+1.6
910,985	+				-0.6
910,985	+				+0.9
910,985	+				+1.2
910,985	+				-1.2
910,986	-				-0.7
911,189	+		Rv0818	0.28	-0.7
911,386	+		Rv0818	0.54	+0.1
911,387	-		Rv0818	0.54	-2.1
911,425	+		Rv0818	0.59	-0.4
911,425	+		Rv0818	0.59	-1.2
911,425	+		Rv0818	0.59	+0.3
911,426	-		Rv0818	0.59	-3.3
911,426	-		Rv0818	0.59	-1.3
911,426	-		Rv0818	0.59	-1.6
911,449	+		Rv0818	0.62	+1.9
911,450	-		Rv0818	0.62	-1.5
911,512	+		Rv0818	0.70	-0.5
911,513	-		Rv0818	0.70	-2.0
911,620	+		Rv0818	0.84	+0.1
911,620	+		Rv0818	0.84	-0.3
911,700	+				+0.2
911,700	+				-0.2
911,700	+				-0.1
911,700	+				+0.0
912,161	+		Rv0819	0.45	+1.9
912,205	-		Rv0819	0.49	-3.0
912,442	-		Rv0819	0.74	-1.2
912,442	-		Rv0819	0.74	-2.9
912,579	+		Rv0819	0.89	-0.7
912,580	-		Rv0819	0.89	-0.1
912,580	-		Rv0819	0.89	-2.5
912,640	-				-3.4
912,678	-				-1.9
912,723	+				-0.4
912,723	+				-2.0
912,724	-				-1.4