Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0676c and Rv0677c overlap by 4 nucleotides Rv0677c and Rv0678 are separated by 84 nucleotides Rv0678 and Rv0679c are separated by 55 nucleotides
Rv0676c: Rv0676c - Probable conserved transmembrane transport protein MmpL5, at 775,586 to 778,480
Rv0676c
Rv0677c: Rv0677c - Possible conserved membrane protein MmpS5, at 778,477 to 778,905
Rv0677c
Rv0678: Rv0678 - Conserved protein, at 778,990 to 779,487
Rv0678
Rv0679c: Rv0679c - Conserved threonine rich protein, at 779,543 to 780,040
Rv0679c
Position (kb) 778
779 Strain fitness (log2 ratio) -5
-4
-3
-2
-1
0
1
2 at 777.489 kb on + strand, within Rv0676c at 777.585 kb on + strand, within Rv0676c at 777.585 kb on + strand, within Rv0676c at 777.651 kb on + strand, within Rv0676c at 777.874 kb on + strand, within Rv0676c at 777.927 kb on + strand, within Rv0676c at 777.927 kb on + strand, within Rv0676c at 777.927 kb on + strand, within Rv0676c at 777.927 kb on + strand, within Rv0676c at 777.928 kb on - strand, within Rv0676c at 777.928 kb on - strand, within Rv0676c at 778.038 kb on + strand, within Rv0676c at 778.304 kb on + strand at 778.393 kb on + strand at 778.393 kb on + strand at 778.394 kb on - strand at 778.394 kb on - strand at 778.694 kb on + strand, within Rv0677c at 778.709 kb on + strand, within Rv0677c at 778.714 kb on - strand, within Rv0677c at 778.977 kb on + strand at 779.263 kb on + strand, within Rv0678 at 779.264 kb on - strand, within Rv0678 at 779.264 kb on - strand, within Rv0678 at 779.264 kb on - strand, within Rv0678 at 779.422 kb on + strand, within Rv0678 at 779.422 kb on + strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.425 kb on - strand, within Rv0678 at 779.459 kb on - strand at 779.797 kb on - strand, within Rv0679c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 777,489 + Rv0676c 0.66 -0.1 777,585 + Rv0676c 0.69 +1.9 777,585 + Rv0676c 0.69 -3.1 777,651 + Rv0676c 0.71 -2.8 777,874 + Rv0676c 0.79 -4.0 777,927 + Rv0676c 0.81 -5.1 777,927 + Rv0676c 0.81 -0.9 777,927 + Rv0676c 0.81 -2.5 777,927 + Rv0676c 0.81 -4.4 777,928 - Rv0676c 0.81 -2.0 777,928 - Rv0676c 0.81 -0.7 778,038 + Rv0676c 0.85 -2.3 778,304 + -3.4 778,393 + -0.1 778,393 + -0.2 778,394 - -3.4 778,394 - -3.9 778,694 + Rv0677c 0.51 -4.5 778,709 + Rv0677c 0.54 -0.2 778,714 - Rv0677c 0.55 -0.5 778,977 + -1.5 779,263 + Rv0678 0.55 +0.9 779,264 - Rv0678 0.55 +1.2 779,264 - Rv0678 0.55 +1.8 779,264 - Rv0678 0.55 +0.9 779,422 + Rv0678 0.87 +1.6 779,422 + Rv0678 0.87 +0.6 779,423 - Rv0678 0.87 +1.0 779,423 - Rv0678 0.87 +1.1 779,423 - Rv0678 0.87 -0.7 779,423 - Rv0678 0.87 +2.5 779,424 + Rv0678 0.87 +0.6 779,424 + Rv0678 0.87 +0.4 779,424 + Rv0678 0.87 -0.7 779,424 + Rv0678 0.87 +1.5 779,425 - Rv0678 0.87 +0.8 779,459 - +0.9 779,797 - Rv0679c 0.51 +1.9
Or see this region's nucleotide sequence