Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0674 and Rv0675 overlap by 4 nucleotides Rv0675 and Rv0676c are separated by 11 nucleotides Rv0676c and Rv0677c overlap by 4 nucleotides Rv0677c and Rv0678 are separated by 84 nucleotides
Rv0674: Rv0674 - Conserved hypothetical protein, at 774,064 to 774,786
Rv0674
Rv0675: Rv0675 - Probable enoyl-CoA hydratase EchA5 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 774,783 to 775,574
Rv0675
Rv0676c: Rv0676c - Probable conserved transmembrane transport protein MmpL5, at 775,586 to 778,480
Rv0676c
Rv0677c: Rv0677c - Possible conserved membrane protein MmpS5, at 778,477 to 778,905
Rv0677c
Rv0678: Rv0678 - Conserved protein, at 778,990 to 779,487
Rv0678
Position (kb) 775
776
777
778
779 Strain fitness (log2 ratio) -6
-5
-4
-3
-2
-1
0
1
2 at 775.492 kb on + strand, within Rv0675 at 775.748 kb on - strand at 775.933 kb on - strand, within Rv0676c at 776.160 kb on + strand, within Rv0676c at 776.160 kb on + strand, within Rv0676c at 776.160 kb on + strand, within Rv0676c at 776.160 kb on + strand, within Rv0676c at 776.160 kb on + strand, within Rv0676c at 776.161 kb on - strand, within Rv0676c at 776.161 kb on - strand, within Rv0676c at 776.161 kb on - strand, within Rv0676c at 776.211 kb on + strand, within Rv0676c at 776.212 kb on - strand, within Rv0676c at 776.412 kb on + strand, within Rv0676c at 776.412 kb on + strand, within Rv0676c at 776.412 kb on + strand, within Rv0676c at 776.413 kb on - strand, within Rv0676c at 776.413 kb on - strand, within Rv0676c at 776.413 kb on - strand, within Rv0676c at 776.706 kb on + strand, within Rv0676c at 776.707 kb on - strand, within Rv0676c at 776.707 kb on - strand, within Rv0676c at 776.770 kb on + strand, within Rv0676c at 776.771 kb on - strand, within Rv0676c at 776.771 kb on - strand, within Rv0676c at 776.771 kb on - strand, within Rv0676c at 776.940 kb on + strand, within Rv0676c at 776.940 kb on + strand, within Rv0676c at 776.940 kb on + strand, within Rv0676c at 776.941 kb on - strand, within Rv0676c at 776.941 kb on - strand, within Rv0676c at 777.109 kb on + strand, within Rv0676c at 777.109 kb on + strand, within Rv0676c at 777.189 kb on + strand, within Rv0676c at 777.190 kb on - strand, within Rv0676c at 777.190 kb on - strand, within Rv0676c at 777.190 kb on - strand, within Rv0676c at 777.222 kb on + strand, within Rv0676c at 777.222 kb on + strand, within Rv0676c at 777.223 kb on - strand, within Rv0676c at 777.223 kb on - strand, within Rv0676c at 777.223 kb on - strand, within Rv0676c at 777.237 kb on + strand, within Rv0676c at 777.237 kb on + strand, within Rv0676c at 777.237 kb on + strand, within Rv0676c at 777.238 kb on - strand, within Rv0676c at 777.489 kb on + strand, within Rv0676c at 777.585 kb on + strand, within Rv0676c at 777.585 kb on + strand, within Rv0676c at 777.651 kb on + strand, within Rv0676c at 777.874 kb on + strand, within Rv0676c at 777.927 kb on + strand, within Rv0676c at 777.927 kb on + strand, within Rv0676c at 777.927 kb on + strand, within Rv0676c at 777.927 kb on + strand, within Rv0676c at 777.928 kb on - strand, within Rv0676c at 777.928 kb on - strand, within Rv0676c at 778.038 kb on + strand, within Rv0676c at 778.304 kb on + strand at 778.393 kb on + strand at 778.393 kb on + strand at 778.394 kb on - strand at 778.394 kb on - strand at 778.694 kb on + strand, within Rv0677c at 778.709 kb on + strand, within Rv0677c at 778.714 kb on - strand, within Rv0677c at 778.977 kb on + strand at 779.263 kb on + strand, within Rv0678 at 779.264 kb on - strand, within Rv0678 at 779.264 kb on - strand, within Rv0678 at 779.264 kb on - strand, within Rv0678 at 779.422 kb on + strand, within Rv0678 at 779.422 kb on + strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.425 kb on - strand, within Rv0678 at 779.459 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 775,492 + Rv0675 0.90 -0.9 775,748 - -1.1 775,933 - Rv0676c 0.12 -3.4 776,160 + Rv0676c 0.20 -3.0 776,160 + Rv0676c 0.20 -2.9 776,160 + Rv0676c 0.20 -1.8 776,160 + Rv0676c 0.20 -4.4 776,160 + Rv0676c 0.20 -4.8 776,161 - Rv0676c 0.20 -1.9 776,161 - Rv0676c 0.20 -3.6 776,161 - Rv0676c 0.20 -3.2 776,211 + Rv0676c 0.22 -1.4 776,212 - Rv0676c 0.22 -1.7 776,412 + Rv0676c 0.29 -1.9 776,412 + Rv0676c 0.29 -5.1 776,412 + Rv0676c 0.29 -1.3 776,413 - Rv0676c 0.29 -4.2 776,413 - Rv0676c 0.29 -3.7 776,413 - Rv0676c 0.29 -1.8 776,706 + Rv0676c 0.39 -4.7 776,707 - Rv0676c 0.39 +1.9 776,707 - Rv0676c 0.39 -6.0 776,770 + Rv0676c 0.41 -5.7 776,771 - Rv0676c 0.41 -2.7 776,771 - Rv0676c 0.41 -3.2 776,771 - Rv0676c 0.41 -5.1 776,940 + Rv0676c 0.47 -3.1 776,940 + Rv0676c 0.47 -3.4 776,940 + Rv0676c 0.47 -1.4 776,941 - Rv0676c 0.47 -2.3 776,941 - Rv0676c 0.47 -4.1 777,109 + Rv0676c 0.53 -5.2 777,109 + Rv0676c 0.53 -4.7 777,189 + Rv0676c 0.55 -3.2 777,190 - Rv0676c 0.55 -0.9 777,190 - Rv0676c 0.55 -4.5 777,190 - Rv0676c 0.55 -1.4 777,222 + Rv0676c 0.57 -0.5 777,222 + Rv0676c 0.57 -3.8 777,223 - Rv0676c 0.57 -5.0 777,223 - Rv0676c 0.57 -2.7 777,223 - Rv0676c 0.57 -1.4 777,237 + Rv0676c 0.57 -1.9 777,237 + Rv0676c 0.57 -5.3 777,237 + Rv0676c 0.57 -1.8 777,238 - Rv0676c 0.57 -3.5 777,489 + Rv0676c 0.66 -0.1 777,585 + Rv0676c 0.69 +1.9 777,585 + Rv0676c 0.69 -3.1 777,651 + Rv0676c 0.71 -2.8 777,874 + Rv0676c 0.79 -4.0 777,927 + Rv0676c 0.81 -5.1 777,927 + Rv0676c 0.81 -0.9 777,927 + Rv0676c 0.81 -2.5 777,927 + Rv0676c 0.81 -4.4 777,928 - Rv0676c 0.81 -2.0 777,928 - Rv0676c 0.81 -0.7 778,038 + Rv0676c 0.85 -2.3 778,304 + -3.4 778,393 + -0.1 778,393 + -0.2 778,394 - -3.4 778,394 - -3.9 778,694 + Rv0677c 0.51 -4.5 778,709 + Rv0677c 0.54 -0.2 778,714 - Rv0677c 0.55 -0.5 778,977 + -1.5 779,263 + Rv0678 0.55 +0.9 779,264 - Rv0678 0.55 +1.2 779,264 - Rv0678 0.55 +1.8 779,264 - Rv0678 0.55 +0.9 779,422 + Rv0678 0.87 +1.6 779,422 + Rv0678 0.87 +0.6 779,423 - Rv0678 0.87 +1.0 779,423 - Rv0678 0.87 +1.1 779,423 - Rv0678 0.87 -0.7 779,423 - Rv0678 0.87 +2.5 779,424 + Rv0678 0.87 +0.6 779,424 + Rv0678 0.87 +0.4 779,424 + Rv0678 0.87 -0.7 779,424 + Rv0678 0.87 +1.5 779,425 - Rv0678 0.87 +0.8 779,459 - +0.9
Or see this region's nucleotide sequence