Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0646c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
739,254	-				+0.2
739,314	-				-0.8
739,329	-				-1.1
739,360	+				-0.2
739,360	+				-2.2
739,361	-				-0.1
739,398	-				+0.1
739,398	-				-0.1
739,398	-				-0.9
739,415	+		Rv0645c	0.10	-1.2
739,415	+		Rv0645c	0.10	+0.1
739,416	-		Rv0645c	0.10	-0.3
739,416	-		Rv0645c	0.10	-0.2
739,462	+		Rv0645c	0.16	+0.0
739,462	+		Rv0645c	0.16	-0.3
739,462	+		Rv0645c	0.16	-0.0
739,496	+		Rv0645c	0.20	-0.5
739,496	+		Rv0645c	0.20	-0.1
739,497	-		Rv0645c	0.20	-0.4
739,676	+		Rv0645c	0.41	-0.5
739,696	+		Rv0645c	0.43	-0.5
739,696	+		Rv0645c	0.43	+0.3
739,696	+		Rv0645c	0.43	-1.4
739,696	+		Rv0645c	0.43	-0.5
739,697	-		Rv0645c	0.43	-0.1
739,728	-		Rv0645c	0.47	-0.1
739,751	+		Rv0645c	0.49	-0.1
739,752	-		Rv0645c	0.49	+0.6
739,752	-		Rv0645c	0.49	-0.2
739,892	+		Rv0645c	0.66	+0.3
739,934	+		Rv0645c	0.70	-0.6
739,935	-		Rv0645c	0.71	+0.0
740,065	-		Rv0645c	0.86	-0.7
740,065	-		Rv0645c	0.86	-0.4
740,094	-		Rv0645c	0.89	-0.9
740,145	-				+0.1
740,166	-				+0.7
740,168	+				+0.3
740,168	+				-0.2
740,168	+				-0.0
740,169	-				+1.1
740,213	+				-1.3
740,213	+				-2.6
740,213	+				-0.3
740,213	+				-0.9
740,214	-				+0.5
740,214	-				+0.0
740,214	-				-1.2
740,214	-				+0.3
740,534	+		Rv0646c	0.33	-0.8
740,854	-		Rv0646c	0.68	-1.1
741,090	+				-0.3
741,090	+				-1.5
741,093	+				-1.7
741,152	+				-1.1