Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0579 and Rv0580c are separated by 128 nucleotides Rv0580c and Rv0581 are separated by 93 nucleotides Rv0581 and Rv0582 overlap by 4 nucleotides Rv0582 and Rv0583c are separated by 59 nucleotides
Rv0579: Rv0579 - Conserved hypothetical protein, at 676,238 to 676,996
Rv0579
Rv0580c: Rv0580c - Conserved protein, at 677,125 to 677,616
Rv0580c
Rv0581: Rv0581 - Possible antitoxin VapB26, at 677,710 to 677,925
Rv0581
Rv0582: Rv0582 - Possible toxin VapC26. Contains PIN domain., at 677,922 to 678,329
Rv0582
Rv0583c: Rv0583c - Probable conserved lipoprotein LpqN, at 678,389 to 679,075
Rv0583c
Position (kb) 677
678 Strain fitness (log2 ratio) -1
0
1
2 at 676.144 kb on + strand at 676.145 kb on - strand at 676.145 kb on - strand at 676.159 kb on - strand at 676.232 kb on + strand at 676.233 kb on - strand at 676.247 kb on + strand at 676.379 kb on - strand, within Rv0579 at 676.460 kb on + strand, within Rv0579 at 676.465 kb on + strand, within Rv0579 at 676.466 kb on - strand, within Rv0579 at 676.523 kb on - strand, within Rv0579 at 676.523 kb on - strand, within Rv0579 at 676.984 kb on + strand at 677.261 kb on + strand, within Rv0580c at 677.627 kb on + strand at 677.680 kb on - strand at 677.859 kb on - strand, within Rv0581 at 677.859 kb on - strand, within Rv0581 at 677.861 kb on - strand, within Rv0581 at 678.555 kb on + strand, within Rv0583c at 678.555 kb on + strand, within Rv0583c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 676,144 + -0.3 676,145 - +1.9 676,145 - -0.3 676,159 - +1.9 676,232 + +1.1 676,233 - -0.4 676,247 + -1.3 676,379 - Rv0579 0.19 -1.0 676,460 + Rv0579 0.29 -0.5 676,465 + Rv0579 0.30 -0.3 676,466 - Rv0579 0.30 +0.9 676,523 - Rv0579 0.38 -0.4 676,523 - Rv0579 0.38 -0.5 676,984 + +0.4 677,261 + Rv0580c 0.28 -1.1 677,627 + -0.8 677,680 - -0.8 677,859 - Rv0581 0.69 -0.4 677,859 - Rv0581 0.69 -0.0 677,861 - Rv0581 0.70 -0.7 678,555 + Rv0583c 0.24 +0.8 678,555 + Rv0583c 0.24 -0.2
Or see this region's nucleotide sequence