Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0575c and Rv0576 are separated by 102 nucleotides Rv0576 and Rv0577 are separated by 13 nucleotides Rv0577 and Rv0578c are separated by 44 nucleotides
Rv0575c: Rv0575c - Possible oxidoreductase, at 668,579 to 669,745
Rv0575c
Rv0576: Rv0576 - Probable transcriptional regulatory protein (possibly ArsR-family), at 669,848 to 671,152
Rv0576
Rv0577: Rv0577 - Conserved protein TB27.3, at 671,166 to 671,951
Rv0577
Rv0578c: Rv0578c - PE-PGRS family protein PE_PGRS7, at 671,996 to 675,916
Rv0578c
Position (kb) 669
670
671
672 Strain fitness (log2 ratio) -2
-1
0
1
2 at 668.881 kb on - strand, within Rv0575c at 669.154 kb on - strand, within Rv0575c at 669.154 kb on - strand, within Rv0575c at 669.162 kb on + strand, within Rv0575c at 669.162 kb on + strand, within Rv0575c at 669.162 kb on + strand, within Rv0575c at 669.162 kb on + strand, within Rv0575c at 669.226 kb on - strand, within Rv0575c at 669.417 kb on + strand, within Rv0575c at 669.418 kb on - strand, within Rv0575c at 669.549 kb on + strand, within Rv0575c at 669.550 kb on - strand, within Rv0575c at 669.627 kb on + strand, within Rv0575c at 669.627 kb on + strand, within Rv0575c at 669.628 kb on - strand, within Rv0575c at 669.888 kb on + strand at 669.889 kb on - strand at 669.919 kb on + strand at 670.029 kb on - strand, within Rv0576 at 670.031 kb on + strand, within Rv0576 at 670.259 kb on - strand, within Rv0576 at 670.309 kb on + strand, within Rv0576 at 670.310 kb on - strand, within Rv0576 at 670.994 kb on + strand, within Rv0576 at 670.998 kb on + strand, within Rv0576 at 671.151 kb on - strand at 671.251 kb on - strand, within Rv0577 at 671.311 kb on - strand, within Rv0577 at 671.311 kb on - strand, within Rv0577 at 671.403 kb on + strand, within Rv0577 at 671.403 kb on + strand, within Rv0577 at 671.403 kb on + strand, within Rv0577 at 671.403 kb on + strand, within Rv0577 at 671.404 kb on - strand, within Rv0577 at 671.404 kb on - strand, within Rv0577 at 671.542 kb on + strand, within Rv0577 at 671.542 kb on + strand, within Rv0577 at 671.687 kb on - strand, within Rv0577 at 671.687 kb on - strand, within Rv0577 at 671.787 kb on + strand, within Rv0577 at 671.949 kb on + strand at 671.949 kb on + strand at 671.950 kb on - strand at 671.997 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 668,881 - Rv0575c 0.26 -1.1 669,154 - Rv0575c 0.49 -0.5 669,154 - Rv0575c 0.49 -0.1 669,162 + Rv0575c 0.50 +2.2 669,162 + Rv0575c 0.50 -0.3 669,162 + Rv0575c 0.50 -0.8 669,162 + Rv0575c 0.50 -1.5 669,226 - Rv0575c 0.55 -0.4 669,417 + Rv0575c 0.72 +0.2 669,418 - Rv0575c 0.72 +0.3 669,549 + Rv0575c 0.83 +0.3 669,550 - Rv0575c 0.83 +0.1 669,627 + Rv0575c 0.90 -2.0 669,627 + Rv0575c 0.90 -0.4 669,628 - Rv0575c 0.90 -0.5 669,888 + -0.2 669,889 - -0.8 669,919 + -0.5 670,029 - Rv0576 0.14 -1.1 670,031 + Rv0576 0.14 -1.4 670,259 - Rv0576 0.31 +0.6 670,309 + Rv0576 0.35 -0.6 670,310 - Rv0576 0.35 -0.6 670,994 + Rv0576 0.88 -1.4 670,998 + Rv0576 0.88 -0.3 671,151 - -0.2 671,251 - Rv0577 0.11 +0.8 671,311 - Rv0577 0.18 -0.5 671,311 - Rv0577 0.18 +0.5 671,403 + Rv0577 0.30 +0.1 671,403 + Rv0577 0.30 -0.2 671,403 + Rv0577 0.30 -0.6 671,403 + Rv0577 0.30 -1.1 671,404 - Rv0577 0.30 +0.6 671,404 - Rv0577 0.30 +0.2 671,542 + Rv0577 0.48 +0.2 671,542 + Rv0577 0.48 -0.3 671,687 - Rv0577 0.66 -1.3 671,687 - Rv0577 0.66 +1.3 671,787 + Rv0577 0.79 -0.4 671,949 + +0.5 671,949 + +0.6 671,950 - +0.4 671,997 + -0.5
Or see this region's nucleotide sequence