Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0570 and Rv0571c are separated by 113 nucleotides Rv0571c and Rv0572c are separated by 223 nucleotides
Rv0570: Rv0570 - Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase), at 661,295 to 663,373
Rv0570
Rv0571c: Rv0571c - Conserved protein, at 663,487 to 664,818
Rv0571c
Rv0572c: Rv0572c - Hypothetical protein, at 665,042 to 665,383
Rv0572c
Position (kb) 663
664
665 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3 at 663.216 kb on - strand at 663.216 kb on - strand at 663.216 kb on - strand at 663.285 kb on + strand at 663.577 kb on + strand at 663.625 kb on + strand, within Rv0571c at 663.626 kb on - strand, within Rv0571c at 664.100 kb on - strand, within Rv0571c at 664.304 kb on + strand, within Rv0571c at 664.504 kb on + strand, within Rv0571c at 664.756 kb on + strand at 664.861 kb on - strand at 664.919 kb on + strand at 664.920 kb on - strand at 664.925 kb on - strand at 664.973 kb on + strand at 665.045 kb on + strand at 665.046 kb on - strand at 665.133 kb on + strand, within Rv0572c at 665.134 kb on - strand, within Rv0572c at 665.134 kb on - strand, within Rv0572c at 665.212 kb on - strand, within Rv0572c at 665.214 kb on + strand, within Rv0572c at 665.214 kb on + strand, within Rv0572c at 665.215 kb on - strand, within Rv0572c at 665.338 kb on + strand, within Rv0572c at 665.339 kb on - strand, within Rv0572c at 665.419 kb on + strand at 665.420 kb on - strand at 665.488 kb on - strand at 665.492 kb on - strand at 665.543 kb on + strand at 665.543 kb on + strand at 665.543 kb on + strand at 665.543 kb on + strand at 665.544 kb on - strand at 665.544 kb on - strand at 665.546 kb on - strand at 665.670 kb on + strand at 665.670 kb on + strand at 665.670 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 663,216 - -0.4 663,216 - -0.5 663,216 - -2.1 663,285 + +0.8 663,577 + -0.8 663,625 + Rv0571c 0.10 +1.9 663,626 - Rv0571c 0.10 +0.5 664,100 - Rv0571c 0.46 +0.2 664,304 + Rv0571c 0.61 -1.5 664,504 + Rv0571c 0.76 -0.1 664,756 + +0.4 664,861 - -1.7 664,919 + -0.8 664,920 - -1.0 664,925 - +2.9 664,973 + -0.0 665,045 + -0.8 665,046 - -0.2 665,133 + Rv0572c 0.27 +0.3 665,134 - Rv0572c 0.27 -0.4 665,134 - Rv0572c 0.27 +0.7 665,212 - Rv0572c 0.50 -0.1 665,214 + Rv0572c 0.50 +1.9 665,214 + Rv0572c 0.50 +1.1 665,215 - Rv0572c 0.51 -1.0 665,338 + Rv0572c 0.87 -0.1 665,339 - Rv0572c 0.87 -3.5 665,419 + +1.1 665,420 - -1.2 665,488 - -0.3 665,492 - +0.4 665,543 + +0.1 665,543 + +0.1 665,543 + -0.4 665,543 + -0.3 665,544 - -0.2 665,544 - +0.1 665,546 - +0.2 665,670 + -0.4 665,670 + +3.3 665,670 + -0.5
Or see this region's nucleotide sequence