Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0530 and Rv0530A overlap by 4 nucleotides Rv0530A and Rv0531 are separated by 46 nucleotides Rv0531 and Rv0532 are separated by 146 nucleotides
Rv0530: Rv0530 - Conserved protein, at 620,907 to 622,124
Rv0530
Rv0530A: Rv0530A - Conserved protein, at 622,121 to 622,282
Rv0530A
Rv0531: Rv0531 - Possible conserved membrane protein, at 622,329 to 622,646
Rv0531
Rv0532: Rv0532 - PE-PGRS family protein PE_PGRS6, at 622,793 to 624,577
Rv0532
Position (kb) 622
623 Strain fitness (log2 ratio) -2
-1
0
1
2 at 621.357 kb on + strand, within Rv0530 at 621.565 kb on - strand, within Rv0530 at 621.666 kb on + strand, within Rv0530 at 621.667 kb on - strand, within Rv0530 at 621.699 kb on + strand, within Rv0530 at 621.699 kb on + strand, within Rv0530 at 621.700 kb on - strand, within Rv0530 at 621.700 kb on - strand, within Rv0530 at 621.700 kb on - strand, within Rv0530 at 621.764 kb on + strand, within Rv0530 at 622.122 kb on + strand at 622.122 kb on + strand at 622.123 kb on - strand at 622.132 kb on + strand at 622.132 kb on + strand at 622.133 kb on - strand at 622.239 kb on + strand, within Rv0530A at 622.240 kb on - strand, within Rv0530A at 622.240 kb on - strand, within Rv0530A at 622.240 kb on - strand, within Rv0530A at 622.240 kb on - strand, within Rv0530A at 622.275 kb on + strand at 622.305 kb on - strand at 622.306 kb on + strand at 622.306 kb on + strand at 622.307 kb on - strand at 622.318 kb on - strand at 622.343 kb on + strand at 622.375 kb on + strand, within Rv0531 at 622.751 kb on + strand at 622.976 kb on + strand, within Rv0532 at 622.977 kb on - strand, within Rv0532 at 623.052 kb on - strand, within Rv0532 at 623.052 kb on - strand, within Rv0532 at 623.052 kb on - strand, within Rv0532 at 623.202 kb on - strand, within Rv0532 at 623.441 kb on + strand, within Rv0532 at 623.441 kb on + strand, within Rv0532
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 621,357 + Rv0530 0.37 -0.6 621,565 - Rv0530 0.54 -1.4 621,666 + Rv0530 0.62 -0.1 621,667 - Rv0530 0.62 +1.9 621,699 + Rv0530 0.65 -0.4 621,699 + Rv0530 0.65 -1.1 621,700 - Rv0530 0.65 -0.1 621,700 - Rv0530 0.65 +0.3 621,700 - Rv0530 0.65 -2.0 621,764 + Rv0530 0.70 +0.2 622,122 + +0.4 622,122 + -0.7 622,123 - +0.7 622,132 + -0.5 622,132 + -0.7 622,133 - +0.3 622,239 + Rv0530A 0.73 -0.1 622,240 - Rv0530A 0.73 +0.2 622,240 - Rv0530A 0.73 -0.6 622,240 - Rv0530A 0.73 -0.7 622,240 - Rv0530A 0.73 -0.3 622,275 + -0.1 622,305 - +1.9 622,306 + -0.6 622,306 + -0.4 622,307 - +0.2 622,318 - -0.2 622,343 + -0.6 622,375 + Rv0531 0.14 -0.9 622,751 + +0.3 622,976 + Rv0532 0.10 -0.1 622,977 - Rv0532 0.10 -0.2 623,052 - Rv0532 0.15 +0.5 623,052 - Rv0532 0.15 -0.0 623,052 - Rv0532 0.15 -0.3 623,202 - Rv0532 0.23 +1.1 623,441 + Rv0532 0.36 -0.2 623,441 + Rv0532 0.36 +0.3
Or see this region's nucleotide sequence