Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0397A and Rv0398c are separated by 36 nucleotides Rv0398c and Rv0399c are separated by 6 nucleotides Rv0399c and Rv0400c are separated by 9 nucleotides
Rv0397A: Rv0397A - Conserved protein, at 476,394 to 476,642
Rv0397A
Rv0398c: Rv0398c - Possible secreted protein, at 476,679 to 477,320
Rv0398c
Rv0399c: Rv0399c - Possible conserved lipoprotein LpqK, at 477,327 to 478,556
Rv0399c
Rv0400c: Rv0400c - Acyl-CoA dehydrogenase FadE7, at 478,566 to 479,753
Rv0400c
Position (kb) 477
478
479 Strain fitness (log2 ratio) -2
-1
0
1 at 476.345 kb on + strand at 476.426 kb on - strand, within Rv0397A at 476.545 kb on + strand, within Rv0397A at 476.546 kb on - strand, within Rv0397A at 476.547 kb on + strand, within Rv0397A at 476.547 kb on + strand, within Rv0397A at 476.681 kb on - strand at 476.767 kb on + strand, within Rv0398c at 476.768 kb on - strand, within Rv0398c at 477.134 kb on + strand, within Rv0398c at 477.324 kb on + strand at 477.328 kb on + strand at 477.329 kb on - strand at 477.391 kb on - strand at 477.393 kb on + strand at 477.393 kb on + strand at 477.488 kb on - strand, within Rv0399c at 477.547 kb on - strand, within Rv0399c at 477.566 kb on - strand, within Rv0399c at 477.656 kb on - strand, within Rv0399c at 478.152 kb on + strand, within Rv0399c at 478.267 kb on + strand, within Rv0399c at 479.497 kb on + strand, within Rv0400c at 479.498 kb on - strand, within Rv0400c at 479.498 kb on - strand, within Rv0400c at 479.498 kb on - strand, within Rv0400c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 476,345 + +0.6 476,426 - Rv0397A 0.13 +0.1 476,545 + Rv0397A 0.61 +0.3 476,546 - Rv0397A 0.61 -0.4 476,547 + Rv0397A 0.61 -0.1 476,547 + Rv0397A 0.61 -1.9 476,681 - -0.4 476,767 + Rv0398c 0.14 -0.4 476,768 - Rv0398c 0.14 -0.2 477,134 + Rv0398c 0.71 -1.5 477,324 + -0.2 477,328 + +0.2 477,329 - -0.6 477,391 - -1.9 477,393 + -0.3 477,393 + +0.2 477,488 - Rv0399c 0.13 -0.4 477,547 - Rv0399c 0.18 -0.5 477,566 - Rv0399c 0.19 -1.9 477,656 - Rv0399c 0.27 -0.4 478,152 + Rv0399c 0.67 +0.8 478,267 + Rv0399c 0.76 -0.4 479,497 + Rv0400c 0.78 -0.1 479,498 - Rv0400c 0.78 +0.3 479,498 - Rv0400c 0.78 -0.2 479,498 - Rv0400c 0.78 -0.1
Or see this region's nucleotide sequence