Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0172 and Rv0173 overlap by 4 nucleotides Rv0173 and Rv0174 overlap by 7 nucleotides
Rv0172: Rv0172 - Mce-family protein Mce1D, at 202,476 to 204,068
Rv0172
Rv0173: Rv0173 - Possible Mce-family lipoprotein LprK (Mce-family lipoprotein Mce1E), at 204,065 to 205,237
Rv0173
Rv0174: Rv0174 - Mce-family protein Mce1F, at 205,231 to 206,778
Rv0174
Position (kb) 204
205
206 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 203.114 kb on - strand, within Rv0172 at 203.143 kb on + strand, within Rv0172 at 203.319 kb on - strand, within Rv0172 at 203.424 kb on + strand, within Rv0172 at 203.425 kb on - strand, within Rv0172 at 203.425 kb on - strand, within Rv0172 at 203.425 kb on - strand, within Rv0172 at 203.689 kb on - strand, within Rv0172 at 203.726 kb on + strand, within Rv0172 at 203.910 kb on + strand at 203.911 kb on - strand at 203.966 kb on - strand at 203.993 kb on - strand at 203.993 kb on - strand at 204.218 kb on + strand, within Rv0173 at 204.227 kb on + strand, within Rv0173 at 204.228 kb on - strand, within Rv0173 at 204.691 kb on + strand, within Rv0173 at 204.728 kb on + strand, within Rv0173 at 204.728 kb on + strand, within Rv0173 at 204.728 kb on + strand, within Rv0173 at 204.728 kb on + strand, within Rv0173 at 204.774 kb on + strand, within Rv0173 at 204.838 kb on - strand, within Rv0173 at 204.950 kb on + strand, within Rv0173 at 204.950 kb on + strand, within Rv0173 at 204.951 kb on - strand, within Rv0173 at 205.028 kb on + strand, within Rv0173 at 205.029 kb on - strand, within Rv0173 at 205.029 kb on - strand, within Rv0173 at 205.062 kb on - strand, within Rv0173 at 205.062 kb on - strand, within Rv0173 at 205.212 kb on + strand at 205.213 kb on - strand at 205.309 kb on + strand at 205.313 kb on - strand at 205.313 kb on - strand at 205.388 kb on - strand, within Rv0174 at 205.416 kb on + strand, within Rv0174 at 205.588 kb on + strand, within Rv0174 at 205.588 kb on + strand, within Rv0174 at 205.589 kb on - strand, within Rv0174 at 205.589 kb on - strand, within Rv0174 at 206.063 kb on - strand, within Rv0174 at 206.180 kb on - strand, within Rv0174
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 203,114 - Rv0172 0.40 -0.9 203,143 + Rv0172 0.42 -1.8 203,319 - Rv0172 0.53 +1.3 203,424 + Rv0172 0.60 -0.6 203,425 - Rv0172 0.60 -1.3 203,425 - Rv0172 0.60 -1.8 203,425 - Rv0172 0.60 -0.2 203,689 - Rv0172 0.76 -1.0 203,726 + Rv0172 0.78 -0.7 203,910 + -1.4 203,911 - -1.0 203,966 - -1.3 203,993 - -1.5 203,993 - -1.1 204,218 + Rv0173 0.13 +2.5 204,227 + Rv0173 0.14 -0.1 204,228 - Rv0173 0.14 +0.2 204,691 + Rv0173 0.53 -1.4 204,728 + Rv0173 0.57 -1.4 204,728 + Rv0173 0.57 -1.7 204,728 + Rv0173 0.57 +0.9 204,728 + Rv0173 0.57 -1.5 204,774 + Rv0173 0.60 -2.5 204,838 - Rv0173 0.66 -2.3 204,950 + Rv0173 0.75 -3.6 204,950 + Rv0173 0.75 -2.7 204,951 - Rv0173 0.76 -0.5 205,028 + Rv0173 0.82 -0.1 205,029 - Rv0173 0.82 -1.9 205,029 - Rv0173 0.82 -0.4 205,062 - Rv0173 0.85 +0.9 205,062 - Rv0173 0.85 -0.7 205,212 + +0.1 205,213 - +1.3 205,309 + +1.3 205,313 - +0.9 205,313 - -0.2 205,388 - Rv0174 0.10 -1.6 205,416 + Rv0174 0.12 -2.6 205,588 + Rv0174 0.23 -1.6 205,588 + Rv0174 0.23 -0.1 205,589 - Rv0174 0.23 +0.7 205,589 - Rv0174 0.23 -1.3 206,063 - Rv0174 0.54 +1.9 206,180 - Rv0174 0.61 -0.7
Or see this region's nucleotide sequence