Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0171 and Rv0172 overlap by 4 nucleotides Rv0172 and Rv0173 overlap by 4 nucleotides
Rv0171: Rv0171 - Mce-family protein Mce1C, at 200,932 to 202,479
Rv0171
Rv0172: Rv0172 - Mce-family protein Mce1D, at 202,476 to 204,068
Rv0172
Rv0173: Rv0173 - Possible Mce-family lipoprotein LprK (Mce-family lipoprotein Mce1E), at 204,065 to 205,237
Rv0173
Position (kb) 202
203
204
205 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 201.518 kb on + strand, within Rv0171 at 201.521 kb on + strand, within Rv0171 at 201.522 kb on - strand, within Rv0171 at 201.581 kb on + strand, within Rv0171 at 201.594 kb on + strand, within Rv0171 at 201.595 kb on - strand, within Rv0171 at 201.595 kb on - strand, within Rv0171 at 201.839 kb on - strand, within Rv0171 at 201.919 kb on - strand, within Rv0171 at 201.961 kb on + strand, within Rv0171 at 201.961 kb on + strand, within Rv0171 at 201.962 kb on - strand, within Rv0171 at 202.494 kb on - strand at 202.676 kb on + strand, within Rv0172 at 202.677 kb on - strand, within Rv0172 at 202.677 kb on - strand, within Rv0172 at 202.758 kb on + strand, within Rv0172 at 202.758 kb on + strand, within Rv0172 at 202.759 kb on - strand, within Rv0172 at 202.759 kb on - strand, within Rv0172 at 202.759 kb on - strand, within Rv0172 at 202.759 kb on - strand, within Rv0172 at 202.839 kb on + strand, within Rv0172 at 202.839 kb on + strand, within Rv0172 at 202.937 kb on + strand, within Rv0172 at 203.031 kb on - strand, within Rv0172 at 203.114 kb on - strand, within Rv0172 at 203.143 kb on + strand, within Rv0172 at 203.319 kb on - strand, within Rv0172 at 203.424 kb on + strand, within Rv0172 at 203.425 kb on - strand, within Rv0172 at 203.425 kb on - strand, within Rv0172 at 203.425 kb on - strand, within Rv0172 at 203.689 kb on - strand, within Rv0172 at 203.726 kb on + strand, within Rv0172 at 203.910 kb on + strand at 203.911 kb on - strand at 203.966 kb on - strand at 203.993 kb on - strand at 203.993 kb on - strand at 204.218 kb on + strand, within Rv0173 at 204.227 kb on + strand, within Rv0173 at 204.228 kb on - strand, within Rv0173 at 204.691 kb on + strand, within Rv0173 at 204.728 kb on + strand, within Rv0173 at 204.728 kb on + strand, within Rv0173 at 204.728 kb on + strand, within Rv0173 at 204.728 kb on + strand, within Rv0173 at 204.774 kb on + strand, within Rv0173 at 204.838 kb on - strand, within Rv0173 at 204.950 kb on + strand, within Rv0173 at 204.950 kb on + strand, within Rv0173 at 204.951 kb on - strand, within Rv0173 at 205.028 kb on + strand, within Rv0173 at 205.029 kb on - strand, within Rv0173 at 205.029 kb on - strand, within Rv0173 at 205.062 kb on - strand, within Rv0173 at 205.062 kb on - strand, within Rv0173
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 201,518 + Rv0171 0.38 -1.7 201,521 + Rv0171 0.38 +0.3 201,522 - Rv0171 0.38 -1.2 201,581 + Rv0171 0.42 -1.0 201,594 + Rv0171 0.43 -1.4 201,595 - Rv0171 0.43 -1.0 201,595 - Rv0171 0.43 -1.0 201,839 - Rv0171 0.59 -1.2 201,919 - Rv0171 0.64 -0.9 201,961 + Rv0171 0.66 -1.5 201,961 + Rv0171 0.66 -1.2 201,962 - Rv0171 0.67 -1.3 202,494 - -1.3 202,676 + Rv0172 0.13 +1.2 202,677 - Rv0172 0.13 -2.0 202,677 - Rv0172 0.13 -1.5 202,758 + Rv0172 0.18 -0.2 202,758 + Rv0172 0.18 -2.5 202,759 - Rv0172 0.18 -0.7 202,759 - Rv0172 0.18 +0.6 202,759 - Rv0172 0.18 -1.6 202,759 - Rv0172 0.18 -1.4 202,839 + Rv0172 0.23 -0.9 202,839 + Rv0172 0.23 +1.9 202,937 + Rv0172 0.29 -1.7 203,031 - Rv0172 0.35 -0.6 203,114 - Rv0172 0.40 -0.9 203,143 + Rv0172 0.42 -1.8 203,319 - Rv0172 0.53 +1.3 203,424 + Rv0172 0.60 -0.6 203,425 - Rv0172 0.60 -1.3 203,425 - Rv0172 0.60 -1.8 203,425 - Rv0172 0.60 -0.2 203,689 - Rv0172 0.76 -1.0 203,726 + Rv0172 0.78 -0.7 203,910 + -1.4 203,911 - -1.0 203,966 - -1.3 203,993 - -1.5 203,993 - -1.1 204,218 + Rv0173 0.13 +2.5 204,227 + Rv0173 0.14 -0.1 204,228 - Rv0173 0.14 +0.2 204,691 + Rv0173 0.53 -1.4 204,728 + Rv0173 0.57 -1.4 204,728 + Rv0173 0.57 -1.7 204,728 + Rv0173 0.57 +0.9 204,728 + Rv0173 0.57 -1.5 204,774 + Rv0173 0.60 -2.5 204,838 - Rv0173 0.66 -2.3 204,950 + Rv0173 0.75 -3.6 204,950 + Rv0173 0.75 -2.7 204,951 - Rv0173 0.76 -0.5 205,028 + Rv0173 0.82 -0.1 205,029 - Rv0173 0.82 -1.9 205,029 - Rv0173 0.82 -0.4 205,062 - Rv0173 0.85 +0.9 205,062 - Rv0173 0.85 -0.7
Or see this region's nucleotide sequence