Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0169 and Rv0170 overlap by 4 nucleotides Rv0170 and Rv0171 overlap by 4 nucleotides
Rv0169: Rv0169 - Mce-family protein Mce1A, at 198,534 to 199,898
Rv0169
Rv0170: Rv0170 - Mce-family protein Mce1B, at 199,895 to 200,935
Rv0170
Rv0171: Rv0171 - Mce-family protein Mce1C, at 200,932 to 202,479
Rv0171
Position (kb) 199
200
201 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1 at 199.351 kb on - strand, within Rv0169 at 199.404 kb on + strand, within Rv0169 at 199.404 kb on + strand, within Rv0169 at 199.405 kb on - strand, within Rv0169 at 199.405 kb on - strand, within Rv0169 at 199.441 kb on - strand, within Rv0169 at 199.460 kb on + strand, within Rv0169 at 199.529 kb on + strand, within Rv0169 at 199.530 kb on - strand, within Rv0169 at 199.530 kb on - strand, within Rv0169 at 199.679 kb on + strand, within Rv0169 at 199.680 kb on - strand, within Rv0169 at 199.680 kb on - strand, within Rv0169 at 199.684 kb on - strand, within Rv0169 at 199.816 kb on - strand at 199.843 kb on - strand at 199.881 kb on - strand at 200.002 kb on + strand, within Rv0170 at 200.097 kb on + strand, within Rv0170 at 200.097 kb on + strand, within Rv0170 at 200.162 kb on + strand, within Rv0170 at 200.162 kb on + strand, within Rv0170 at 200.421 kb on + strand, within Rv0170 at 200.563 kb on + strand, within Rv0170 at 200.702 kb on + strand, within Rv0170 at 200.832 kb on - strand at 201.104 kb on + strand, within Rv0171 at 201.437 kb on - strand, within Rv0171 at 201.437 kb on - strand, within Rv0171 at 201.472 kb on - strand, within Rv0171 at 201.518 kb on + strand, within Rv0171 at 201.521 kb on + strand, within Rv0171 at 201.522 kb on - strand, within Rv0171 at 201.581 kb on + strand, within Rv0171 at 201.594 kb on + strand, within Rv0171 at 201.595 kb on - strand, within Rv0171 at 201.595 kb on - strand, within Rv0171 at 201.839 kb on - strand, within Rv0171 at 201.919 kb on - strand, within Rv0171
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 199,351 - Rv0169 0.60 -1.1 199,404 + Rv0169 0.64 -1.5 199,404 + Rv0169 0.64 -2.2 199,405 - Rv0169 0.64 -1.9 199,405 - Rv0169 0.64 -1.6 199,441 - Rv0169 0.66 +0.0 199,460 + Rv0169 0.68 -0.9 199,529 + Rv0169 0.73 -1.9 199,530 - Rv0169 0.73 -0.3 199,530 - Rv0169 0.73 -4.4 199,679 + Rv0169 0.84 -0.9 199,680 - Rv0169 0.84 -0.6 199,680 - Rv0169 0.84 -1.5 199,684 - Rv0169 0.84 -1.4 199,816 - -0.4 199,843 - -2.0 199,881 - -1.2 200,002 + Rv0170 0.10 -1.1 200,097 + Rv0170 0.19 -0.8 200,097 + Rv0170 0.19 -0.1 200,162 + Rv0170 0.26 -1.1 200,162 + Rv0170 0.26 -1.8 200,421 + Rv0170 0.51 -2.3 200,563 + Rv0170 0.64 -1.2 200,702 + Rv0170 0.78 -0.5 200,832 - -2.4 201,104 + Rv0171 0.11 -1.2 201,437 - Rv0171 0.33 -2.0 201,437 - Rv0171 0.33 -0.1 201,472 - Rv0171 0.35 +0.3 201,518 + Rv0171 0.38 -1.7 201,521 + Rv0171 0.38 +0.3 201,522 - Rv0171 0.38 -1.2 201,581 + Rv0171 0.42 -1.0 201,594 + Rv0171 0.43 -1.4 201,595 - Rv0171 0.43 -1.0 201,595 - Rv0171 0.43 -1.0 201,839 - Rv0171 0.59 -1.2 201,919 - Rv0171 0.64 -0.9
Or see this region's nucleotide sequence