Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0075 and Rv0076c are separated by 14 nucleotides Rv0076c and Rv0077c are separated by 63 nucleotides Rv0077c and Rv0078 are separated by 61 nucleotides
Rv0075: Rv0075 - Probable aminotransferase, at 83,996 to 85,168
Rv0075
Rv0076c: Rv0076c - Probable membrane protein, at 85,183 to 85,572
Rv0076c
Rv0077c: Rv0077c - Probable oxidoreductase, at 85,636 to 86,466
Rv0077c
Rv0078: Rv0078 - Probable transcriptional regulatory protein, at 86,528 to 87,133
Rv0078
Position (kb) 85
86 Strain fitness (log2 ratio) -1
0
1
2 at 84.234 kb on - strand, within Rv0075 at 84.353 kb on + strand, within Rv0075 at 84.353 kb on + strand, within Rv0075 at 84.353 kb on + strand, within Rv0075 at 84.353 kb on + strand, within Rv0075 at 84.494 kb on - strand, within Rv0075 at 84.494 kb on - strand, within Rv0075 at 84.544 kb on - strand, within Rv0075 at 84.544 kb on - strand, within Rv0075 at 84.544 kb on - strand, within Rv0075 at 84.743 kb on - strand, within Rv0075 at 84.834 kb on - strand, within Rv0075 at 84.834 kb on - strand, within Rv0075 at 84.918 kb on + strand, within Rv0075 at 84.919 kb on - strand, within Rv0075 at 84.919 kb on - strand, within Rv0075 at 84.952 kb on + strand, within Rv0075 at 84.953 kb on - strand, within Rv0075 at 84.956 kb on + strand, within Rv0075 at 84.956 kb on + strand, within Rv0075 at 84.957 kb on - strand, within Rv0075 at 85.011 kb on - strand, within Rv0075 at 85.167 kb on - strand at 85.223 kb on + strand, within Rv0076c at 85.224 kb on - strand, within Rv0076c at 85.224 kb on - strand, within Rv0076c at 85.224 kb on - strand, within Rv0076c at 85.276 kb on + strand, within Rv0076c at 85.301 kb on - strand, within Rv0076c at 85.576 kb on - strand at 85.576 kb on - strand at 85.721 kb on - strand, within Rv0077c at 86.104 kb on - strand, within Rv0077c at 86.359 kb on + strand, within Rv0077c at 86.359 kb on + strand, within Rv0077c at 86.360 kb on - strand, within Rv0077c at 86.378 kb on + strand, within Rv0077c at 86.430 kb on - strand at 86.436 kb on + strand at 86.448 kb on + strand at 86.528 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 84,234 - Rv0075 0.20 +1.0 84,353 + Rv0075 0.30 -0.3 84,353 + Rv0075 0.30 +0.0 84,353 + Rv0075 0.30 -0.3 84,353 + Rv0075 0.30 +1.9 84,494 - Rv0075 0.42 -1.5 84,494 - Rv0075 0.42 -1.1 84,544 - Rv0075 0.47 -0.2 84,544 - Rv0075 0.47 -0.0 84,544 - Rv0075 0.47 -0.1 84,743 - Rv0075 0.64 +0.0 84,834 - Rv0075 0.71 +1.7 84,834 - Rv0075 0.71 -0.4 84,918 + Rv0075 0.79 -0.0 84,919 - Rv0075 0.79 +0.1 84,919 - Rv0075 0.79 +0.0 84,952 + Rv0075 0.82 -0.3 84,953 - Rv0075 0.82 -0.3 84,956 + Rv0075 0.82 -1.2 84,956 + Rv0075 0.82 -0.6 84,957 - Rv0075 0.82 +1.2 85,011 - Rv0075 0.87 -0.5 85,167 - +0.9 85,223 + Rv0076c 0.10 +0.2 85,224 - Rv0076c 0.11 +0.8 85,224 - Rv0076c 0.11 -0.2 85,224 - Rv0076c 0.11 +1.9 85,276 + Rv0076c 0.24 +0.9 85,301 - Rv0076c 0.30 +0.0 85,576 - -0.8 85,576 - +2.3 85,721 - Rv0077c 0.10 -0.4 86,104 - Rv0077c 0.56 -0.9 86,359 + Rv0077c 0.87 -0.2 86,359 + Rv0077c 0.87 -0.2 86,360 - Rv0077c 0.87 -0.4 86,378 + Rv0077c 0.89 -0.2 86,430 - -0.2 86,436 + +0.6 86,448 + -0.3 86,528 - -0.3
Or see this region's nucleotide sequence