Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3223c

Experiment: 7H9 with Rifampicin 0.014 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Rifampicin 0.014 ug/mL
3,597,985	-				-0.4
3,598,003	+				-0.5
3,598,003	+				+1.1
3,598,003	+				-0.3
3,598,039	+				-0.3
3,598,789	-		Rv3222c	0.79	-0.5
3,598,789	-		Rv3222c	0.79	-0.2
3,599,082	+		Rv3223c	0.28	-0.0
3,599,083	-		Rv3223c	0.28	-1.3
3,599,153	+		Rv3223c	0.39	-0.8
3,599,271	+		Rv3223c	0.57	-0.9
3,599,283	+		Rv3223c	0.59	-0.2
3,599,284	-		Rv3223c	0.59	-0.9
3,599,284	-		Rv3223c	0.59	+0.7
3,599,356	-		Rv3223c	0.70	-0.6
3,599,356	-		Rv3223c	0.70	-1.9
3,599,431	-		Rv3223c	0.81	+1.7
3,599,431	-		Rv3223c	0.81	-0.3
3,599,559	-				-1.7
3,599,559	-				-0.6
3,599,690	+				+0.9
3,599,690	+				-1.2
3,599,691	-				-0.1
3,599,691	-				+1.7
3,599,691	-				-0.6
3,599,778	+				+0.2
3,600,123	+		Rv3224	0.32	-1.1
3,600,124	-		Rv3224	0.32	-0.3
3,600,124	-		Rv3224	0.32	-1.2
3,600,124	-		Rv3224	0.32	+0.9
3,600,155	+		Rv3224	0.36	-0.4
3,600,155	+		Rv3224	0.36	+0.4
3,600,156	-		Rv3224	0.36	-0.1
3,600,223	+		Rv3224	0.44	-0.4
3,600,223	+		Rv3224	0.44	-1.7
3,600,224	-		Rv3224	0.44	-0.2
3,600,224	-		Rv3224	0.44	-0.6
3,600,224	-		Rv3224	0.44	-0.3
3,600,224	-		Rv3224	0.44	+0.6
3,600,230	+		Rv3224	0.45	-0.3
3,600,231	-		Rv3224	0.45	-0.3
3,600,252	+		Rv3224	0.47	+0.9
3,600,252	+		Rv3224	0.47	+0.7
3,600,253	-		Rv3224	0.47	-1.8
3,600,253	-		Rv3224	0.47	+0.5
3,600,334	+		Rv3224	0.57	-0.2
3,600,334	+		Rv3224	0.57	-0.3
3,600,335	-		Rv3224	0.57	+0.8
3,600,335	-		Rv3224	0.57	+0.4
3,600,335	-		Rv3224	0.57	-0.3
3,600,335	-		Rv3224	0.57	+0.2
3,600,349	+		Rv3224	0.59	-0.5
3,600,349	+		Rv3224	0.59	-0.6
3,600,349	+		Rv3224	0.59	-0.5
3,600,507	-		Rv3224	0.77	+0.2
3,600,507	-		Rv3224	0.77	-0.3
3,600,508	+		Rv3224	0.77	+0.8
3,600,508	+		Rv3224	0.77	-0.5
3,600,508	+		Rv3224	0.77	-0.2
3,600,509	-		Rv3224	0.78	-0.6
3,600,523	+		Rv3224	0.79	+0.6
3,600,523	+		Rv3224	0.79	+0.1
3,600,523	+		Rv3224	0.79	+0.1
3,600,524	-		Rv3224	0.79	+0.1