Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2132

Experiment: 7H9 with Rifampicin 0.014 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2130c and Rv2131c are separated by 57 nucleotidesRv2131c and Rv2132 are separated by 90 nucleotidesRv2132 and Rv2133c are separated by 209 nucleotides Rv2130c: Rv2130c - Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC, at 2,391,215 to 2,392,459 Rv2130c Rv2131c: Rv2131c - Monophosphatase CysQ, at 2,392,517 to 2,393,320 Rv2131c Rv2132: Rv2132 - Conserved hypothetical protein, at 2,393,411 to 2,393,641 Rv2132 Rv2133c: Rv2133c - Conserved hypothetical protein, at 2,393,851 to 2,394,639 Rv2133c Position (kb) 2393 2394Strain fitness (log2 ratio) -1 0 1at 2393.564 kb on + strand, within Rv2132at 2393.565 kb on - strand, within Rv2132at 2393.565 kb on - strand, within Rv2132at 2393.588 kb on + strand, within Rv2132at 2393.639 kb on + strandat 2393.852 kb on + strandat 2393.852 kb on + strandat 2394.120 kb on - strand, within Rv2133cat 2394.120 kb on - strand, within Rv2133cat 2394.177 kb on + strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.178 kb on - strand, within Rv2133cat 2394.258 kb on - strand, within Rv2133cat 2394.379 kb on + strand, within Rv2133cat 2394.379 kb on + strand, within Rv2133cat 2394.379 kb on + strand, within Rv2133cat 2394.380 kb on - strand, within Rv2133cat 2394.380 kb on - strand, within Rv2133cat 2394.388 kb on + strand, within Rv2133cat 2394.389 kb on - strand, within Rv2133cat 2394.533 kb on + strand, within Rv2133c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.014 ug/mL
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2,393,564 + Rv2132 0.66 -1.2
2,393,565 - Rv2132 0.67 -0.2
2,393,565 - Rv2132 0.67 -1.4
2,393,588 + Rv2132 0.77 -1.2
2,393,639 + +0.7
2,393,852 + +1.5
2,393,852 + -1.1
2,394,120 - Rv2133c 0.34 +0.1
2,394,120 - Rv2133c 0.34 -0.6
2,394,177 + Rv2133c 0.41 -0.3
2,394,178 - Rv2133c 0.41 -0.3
2,394,178 - Rv2133c 0.41 -0.3
2,394,178 - Rv2133c 0.41 +1.7
2,394,178 - Rv2133c 0.41 -0.4
2,394,178 - Rv2133c 0.41 -0.3
2,394,258 - Rv2133c 0.52 -1.1
2,394,379 + Rv2133c 0.67 -0.4
2,394,379 + Rv2133c 0.67 -0.1
2,394,379 + Rv2133c 0.67 +0.2
2,394,380 - Rv2133c 0.67 -0.1
2,394,380 - Rv2133c 0.67 -1.0
2,394,388 + Rv2133c 0.68 -0.6
2,394,389 - Rv2133c 0.68 +0.1
2,394,533 + Rv2133c 0.86 +1.7

Or see this region's nucleotide sequence