Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1486c

Experiment: 7H9 with Rifampicin 0.014 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1485 and Rv1486c overlap by 35 nucleotidesRv1486c and Rv1487 are separated by 57 nucleotidesRv1487 and Rv1488 are separated by 21 nucleotides Rv1485: Rv1485 - Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase), at 1,675,017 to 1,676,051 Rv1485 Rv1486c: Rv1486c - Conserved hypothetical protein, at 1,676,017 to 1,676,883 Rv1486c Rv1487: Rv1487 - Conserved membrane protein, at 1,676,941 to 1,677,375 Rv1487 Rv1488: Rv1488 - Possible exported conserved protein, at 1,677,397 to 1,678,542 Rv1488 Position (kb) 1676 1677Strain fitness (log2 ratio) -1 0 1 2 3 4at 1676.304 kb on + strand, within Rv1486cat 1676.304 kb on + strand, within Rv1486cat 1676.305 kb on - strand, within Rv1486cat 1676.305 kb on - strand, within Rv1486cat 1676.387 kb on + strand, within Rv1486cat 1676.387 kb on + strand, within Rv1486cat 1676.388 kb on - strand, within Rv1486cat 1676.420 kb on + strand, within Rv1486cat 1676.421 kb on - strand, within Rv1486cat 1676.421 kb on - strand, within Rv1486cat 1676.762 kb on + strand, within Rv1486cat 1676.896 kb on + strandat 1676.896 kb on + strandat 1676.930 kb on - strandat 1676.935 kb on - strandat 1677.053 kb on + strand, within Rv1487at 1677.204 kb on + strand, within Rv1487at 1677.204 kb on + strand, within Rv1487at 1677.204 kb on + strand, within Rv1487at 1677.205 kb on - strand, within Rv1487at 1677.373 kb on + strandat 1677.374 kb on - strandat 1677.525 kb on + strand, within Rv1488at 1677.525 kb on + strand, within Rv1488at 1677.526 kb on - strand, within Rv1488at 1677.526 kb on - strand, within Rv1488at 1677.676 kb on + strand, within Rv1488at 1677.677 kb on - strand, within Rv1488at 1677.710 kb on - strand, within Rv1488at 1677.724 kb on + strand, within Rv1488at 1677.724 kb on + strand, within Rv1488at 1677.725 kb on - strand, within Rv1488at 1677.725 kb on - strand, within Rv1488at 1677.725 kb on - strand, within Rv1488at 1677.725 kb on - strand, within Rv1488

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.014 ug/mL
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1,676,304 + Rv1486c 0.33 -0.4
1,676,304 + Rv1486c 0.33 +1.0
1,676,305 - Rv1486c 0.33 -0.4
1,676,305 - Rv1486c 0.33 +0.2
1,676,387 + Rv1486c 0.43 +0.8
1,676,387 + Rv1486c 0.43 +1.0
1,676,388 - Rv1486c 0.43 +1.1
1,676,420 + Rv1486c 0.46 -0.5
1,676,421 - Rv1486c 0.47 +0.2
1,676,421 - Rv1486c 0.47 +4.7
1,676,762 + Rv1486c 0.86 +0.3
1,676,896 + +0.1
1,676,896 + -0.9
1,676,930 - -0.0
1,676,935 - -0.0
1,677,053 + Rv1487 0.26 +0.1
1,677,204 + Rv1487 0.60 +0.4
1,677,204 + Rv1487 0.60 -0.3
1,677,204 + Rv1487 0.60 -1.0
1,677,205 - Rv1487 0.61 -0.1
1,677,373 + +0.2
1,677,374 - +2.7
1,677,525 + Rv1488 0.11 -1.0
1,677,525 + Rv1488 0.11 -0.1
1,677,526 - Rv1488 0.11 -0.8
1,677,526 - Rv1488 0.11 +0.1
1,677,676 + Rv1488 0.24 +1.2
1,677,677 - Rv1488 0.24 +0.2
1,677,710 - Rv1488 0.27 +1.7
1,677,724 + Rv1488 0.29 +0.1
1,677,724 + Rv1488 0.29 -0.1
1,677,725 - Rv1488 0.29 -0.2
1,677,725 - Rv1488 0.29 +0.3
1,677,725 - Rv1488 0.29 -0.6
1,677,725 - Rv1488 0.29 -0.9

Or see this region's nucleotide sequence