Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1369c

Experiment: 7H9 with Rifampicin 0.014 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1368 and Rv1369c are separated by 188 nucleotidesRv1369c and Rv1370c overlap by 52 nucleotidesRv1370c and Rv1371 are separated by 103 nucleotides Rv1368: Rv1368 - Probable conserved lipoprotein LprF, at 1,541,020 to 1,541,805 Rv1368 Rv1369c: Rv1369c - Probable transposase, at 1,541,994 to 1,542,980 Rv1369c Rv1370c: Rv1370c - Putative transposase for insertion sequence element IS6110 (fragment), at 1,542,929 to 1,543,255 Rv1370c Rv1371: Rv1371 - Probable conserved membrane protein, at 1,543,359 to 1,544,828 Rv1371 Position (kb) 1541 1542 1543Strain fitness (log2 ratio) -1 0 1 2at 1541.262 kb on - strand, within Rv1368at 1541.438 kb on - strand, within Rv1368at 1541.438 kb on - strand, within Rv1368at 1541.467 kb on + strand, within Rv1368at 1541.467 kb on + strand, within Rv1368at 1541.467 kb on + strand, within Rv1368at 1541.468 kb on - strand, within Rv1368at 1541.468 kb on - strand, within Rv1368at 1541.468 kb on - strand, within Rv1368at 1541.630 kb on + strand, within Rv1368at 1541.630 kb on + strand, within Rv1368at 1541.631 kb on - strand, within Rv1368at 1541.631 kb on - strand, within Rv1368at 1541.635 kb on - strand, within Rv1368at 1541.635 kb on - strand, within Rv1368at 1541.635 kb on - strand, within Rv1368at 1543.355 kb on - strandat 1543.355 kb on - strandat 1543.468 kb on - strandat 1543.484 kb on + strandat 1543.561 kb on - strand, within Rv1371at 1543.606 kb on - strand, within Rv1371at 1543.631 kb on + strand, within Rv1371

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.014 ug/mL
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1,541,262 - Rv1368 0.31 -0.4
1,541,438 - Rv1368 0.53 +1.3
1,541,438 - Rv1368 0.53 +0.7
1,541,467 + Rv1368 0.57 -1.1
1,541,467 + Rv1368 0.57 -1.0
1,541,467 + Rv1368 0.57 +2.7
1,541,468 - Rv1368 0.57 -0.2
1,541,468 - Rv1368 0.57 +0.1
1,541,468 - Rv1368 0.57 -0.8
1,541,630 + Rv1368 0.78 +0.6
1,541,630 + Rv1368 0.78 -0.3
1,541,631 - Rv1368 0.78 -1.1
1,541,631 - Rv1368 0.78 +0.3
1,541,635 - Rv1368 0.78 -0.2
1,541,635 - Rv1368 0.78 -0.0
1,541,635 - Rv1368 0.78 -0.5
1,543,355 - -0.4
1,543,355 - -0.2
1,543,468 - +0.6
1,543,484 + +0.1
1,543,561 - Rv1371 0.14 -0.7
1,543,606 - Rv1371 0.17 -0.2
1,543,631 + Rv1371 0.19 -0.4

Or see this region's nucleotide sequence