Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0787

Experiment: 7H9 with Rifampicin 0.014 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0785 and Rv0786c are separated by 34 nucleotidesRv0786c and Rv0787 overlap by 6 nucleotidesRv0787 and Rv0787A are separated by 105 nucleotidesRv0787A and Rv0788 overlap by 4 nucleotides Rv0785: Rv0785 - Conserved protein, at 879,340 to 881,040 Rv0785 Rv0786c: Rv0786c - Conserved protein, at 881,075 to 881,464 Rv0786c Rv0787: Rv0787 - Unknown protein, at 881,459 to 882,418 Rv0787 Rv0787A: Rv0787A - Conserved protein, at 882,524 to 882,763 Rv0787A Rv0788: Rv0788 - Probable phosphoribosylformylglycinamidine synthase I PURG (FGAM synthase I), at 882,760 to 883,434 Rv0788 Position (kb) 881 882 883Strain fitness (log2 ratio) -2 -1 0 1at 880.683 kb on + strand, within Rv0785at 880.684 kb on - strand, within Rv0785at 880.732 kb on + strand, within Rv0785at 881.064 kb on + strandat 881.065 kb on - strandat 881.145 kb on + strand, within Rv0786cat 881.148 kb on + strand, within Rv0786cat 881.358 kb on + strand, within Rv0786cat 881.638 kb on + strand, within Rv0787at 881.812 kb on + strand, within Rv0787at 881.866 kb on + strand, within Rv0787at 882.257 kb on + strand, within Rv0787at 882.258 kb on - strand, within Rv0787at 882.263 kb on + strand, within Rv0787at 882.264 kb on - strand, within Rv0787at 882.344 kb on - strandat 882.398 kb on + strandat 882.399 kb on - strandat 882.443 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.014 ug/mL
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880,683 + Rv0785 0.79 -0.3
880,684 - Rv0785 0.79 -0.6
880,732 + Rv0785 0.82 +0.5
881,064 + -0.3
881,065 - -0.9
881,145 + Rv0786c 0.18 -0.3
881,148 + Rv0786c 0.19 +0.2
881,358 + Rv0786c 0.73 -0.1
881,638 + Rv0787 0.19 +0.3
881,812 + Rv0787 0.37 -0.7
881,866 + Rv0787 0.42 -1.6
882,257 + Rv0787 0.83 +0.7
882,258 - Rv0787 0.83 -0.8
882,263 + Rv0787 0.84 -1.0
882,264 - Rv0787 0.84 -0.5
882,344 - -0.3
882,398 + -0.2
882,399 - -0.7
882,443 - -2.7

Or see this region's nucleotide sequence