Experiment: 7H9 with Rifampicin 0.014 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0387c and Rv0388c are separated by 52 nucleotides Rv0388c and Rv0389 are separated by 333 nucleotides Rv0389 and Rv0390 overlap by 4 nucleotides Rv0390 and Rv0391 overlap by 4 nucleotides
Rv0387c: Rv0387c - Conserved hypothetical protein, at 466,672 to 467,406
Rv0387c
Rv0388c: Rv0388c - PPE family protein PPE9, at 467,459 to 468,001
Rv0388c
Rv0389: Rv0389 - Probable phosphoribosylglycinamide formyltransferase 2 PurT (GART 2) (gar transformylase 2) (5'-phosphoribosylglycinamide transformylase 2) (formate-dependent gar transformylase), at 468,335 to 469,594
Rv0389
Rv0390: Rv0390 - Conserved protein, at 469,591 to 470,013
Rv0390
Rv0391: Rv0391 - Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase), at 470,010 to 471,230
Rv0391
Position (kb) 468
469
470 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 467.396 kb on - strand at 467.396 kb on - strand at 467.396 kb on - strand at 467.431 kb on + strand at 467.432 kb on - strand at 467.596 kb on + strand, within Rv0388c at 467.701 kb on - strand, within Rv0388c at 467.787 kb on + strand, within Rv0388c at 467.787 kb on + strand, within Rv0388c at 467.788 kb on - strand, within Rv0388c at 467.868 kb on + strand, within Rv0388c at 467.955 kb on + strand at 467.955 kb on + strand at 467.955 kb on + strand at 468.139 kb on + strand at 468.140 kb on - strand at 468.140 kb on - strand at 468.140 kb on - strand at 468.140 kb on - strand at 468.140 kb on - strand at 468.140 kb on - strand at 468.140 kb on - strand at 468.143 kb on + strand at 468.143 kb on + strand at 468.185 kb on - strand at 468.247 kb on + strand at 468.296 kb on + strand at 468.296 kb on + strand at 468.296 kb on + strand at 468.297 kb on - strand at 468.504 kb on - strand, within Rv0389 at 469.069 kb on + strand, within Rv0389 at 469.070 kb on - strand, within Rv0389 at 469.070 kb on - strand, within Rv0389 at 469.235 kb on + strand, within Rv0389 at 469.235 kb on + strand, within Rv0389 at 469.235 kb on + strand, within Rv0389 at 469.236 kb on - strand, within Rv0389 at 469.597 kb on + strand at 469.598 kb on - strand at 469.608 kb on + strand at 469.738 kb on + strand, within Rv0390 at 469.738 kb on + strand, within Rv0390 at 469.738 kb on + strand, within Rv0390 at 469.738 kb on + strand, within Rv0390 at 469.839 kb on + strand, within Rv0390 at 469.916 kb on - strand, within Rv0390 at 469.916 kb on - strand, within Rv0390 at 470.130 kb on + strand at 470.146 kb on - strand, within Rv0391 at 470.152 kb on - strand, within Rv0391 at 470.202 kb on + strand, within Rv0391 at 470.202 kb on + strand, within Rv0391 at 470.203 kb on - strand, within Rv0391 at 470.208 kb on + strand, within Rv0391 at 470.208 kb on + strand, within Rv0391
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.014 ug/mL remove 467,396 - +0.5 467,396 - -0.2 467,396 - +0.0 467,431 + -0.6 467,432 - -1.4 467,596 + Rv0388c 0.25 -0.5 467,701 - Rv0388c 0.45 +0.2 467,787 + Rv0388c 0.60 -0.8 467,787 + Rv0388c 0.60 -0.1 467,788 - Rv0388c 0.61 -0.1 467,868 + Rv0388c 0.75 -0.7 467,955 + -1.4 467,955 + +0.1 467,955 + -0.7 468,139 + +0.2 468,140 - +0.1 468,140 - -0.4 468,140 - -0.8 468,140 - -0.8 468,140 - -0.0 468,140 - -0.9 468,140 - -0.1 468,143 + +0.8 468,143 + -0.6 468,185 - -1.1 468,247 + -0.3 468,296 + -0.3 468,296 + -0.5 468,296 + -0.9 468,297 - -0.7 468,504 - Rv0389 0.13 -0.7 469,069 + Rv0389 0.58 +0.6 469,070 - Rv0389 0.58 -0.3 469,070 - Rv0389 0.58 +0.2 469,235 + Rv0389 0.71 -1.3 469,235 + Rv0389 0.71 -0.8 469,235 + Rv0389 0.71 -0.4 469,236 - Rv0389 0.72 -0.2 469,597 + +0.2 469,598 - -3.0 469,608 + +1.7 469,738 + Rv0390 0.35 -0.7 469,738 + Rv0390 0.35 +2.0 469,738 + Rv0390 0.35 -1.3 469,738 + Rv0390 0.35 -0.6 469,839 + Rv0390 0.59 +0.9 469,916 - Rv0390 0.77 -0.6 469,916 - Rv0390 0.77 -1.0 470,130 + -0.2 470,146 - Rv0391 0.11 -0.2 470,152 - Rv0391 0.12 -1.6 470,202 + Rv0391 0.16 +0.3 470,202 + Rv0391 0.16 +0.0 470,203 - Rv0391 0.16 +0.2 470,208 + Rv0391 0.16 -0.4 470,208 + Rv0391 0.16 -0.1
Or see this region's nucleotide sequence