Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2360c

Experiment: 7H9 with Rifampicin 0.014 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2358 and Rv2359 overlap by 4 nucleotidesRv2359 and Rv2360c are separated by 107 nucleotidesRv2360c and Rv2361c overlap by 1 nucleotidesRv2361c and Rv2362c overlap by 8 nucleotides Rv2358: Rv2358 - Probable transcriptional regulatory protein SmtB (probably ArsR-family), at 2,641,246 to 2,641,653 Rv2358 Rv2359: Rv2359 - Probable zinc uptake regulation protein Zur, at 2,641,650 to 2,642,042 Rv2359 Rv2360c: Rv2360c - Unknown protein, at 2,642,150 to 2,642,578 Rv2360c Rv2361c: Rv2361c - Long (C50) chain Z-isoprenyl diphosphate synthase (Z-decaprenyl diphosphate synthase), at 2,642,578 to 2,643,468 Rv2361c Rv2362c: Rv2362c - Possible DNA repair protein RecO, at 2,643,461 to 2,644,258 Rv2362c Position (kb) 2642 2643Strain fitness (log2 ratio) -2 -1 0 1at 2641.154 kb on - strandat 2641.213 kb on + strandat 2641.213 kb on + strandat 2641.213 kb on + strandat 2641.216 kb on + strandat 2641.245 kb on + strandat 2641.245 kb on + strandat 2641.304 kb on + strand, within Rv2358at 2641.304 kb on + strand, within Rv2358at 2641.379 kb on + strand, within Rv2358at 2642.483 kb on - strand, within Rv2360cat 2642.483 kb on - strand, within Rv2360cat 2642.579 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.014 ug/mL
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2,641,154 - -2.0
2,641,213 + +0.0
2,641,213 + -0.1
2,641,213 + +0.0
2,641,216 + -0.3
2,641,245 + -0.6
2,641,245 + -1.0
2,641,304 + Rv2358 0.14 -0.5
2,641,304 + Rv2358 0.14 -0.5
2,641,379 + Rv2358 0.33 +0.3
2,642,483 - Rv2360c 0.78 +0.1
2,642,483 - Rv2360c 0.78 +0.7
2,642,579 + -0.2

Or see this region's nucleotide sequence