Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2307A

Experiment: 7H9 with Rifampicin 0.014 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Rifampicin 0.014 ug/mL
2,578,242	+		Rv2307c	0.46	-1.1
2,578,242	+		Rv2307c	0.46	-0.1
2,578,469	-		Rv2307c	0.73	-0.5
2,578,491	+		Rv2307c	0.76	+0.7
2,578,492	-		Rv2307c	0.76	+2.3
2,578,492	-		Rv2307c	0.76	+0.2
2,578,492	-		Rv2307c	0.76	+0.2
2,578,492	-		Rv2307c	0.76	-0.3
2,578,593	+		Rv2307c	0.88	-0.8
2,578,593	+		Rv2307c	0.88	-0.5
2,578,594	-		Rv2307c	0.88	-0.7
2,578,594	-		Rv2307c	0.88	-0.2
2,578,594	-		Rv2307c	0.88	-1.1
2,578,594	-		Rv2307c	0.88	-0.3
2,578,627	+				-0.1
2,578,627	+				-0.1
2,578,628	-				+1.7
2,578,628	-				-1.1
2,578,628	-				+0.3
2,578,658	-				-1.5
2,578,698	+				+0.1
2,578,698	+				+0.3
2,578,699	-				-0.3
2,578,921	-				+0.2
2,578,921	-				+1.0
2,578,994	+				+2.7
2,578,994	+				-0.9
2,578,995	-				-0.8
2,578,995	-				-0.8
2,579,019	+				+1.3
2,579,019	+				-0.1
2,579,020	-				+0.0
2,579,020	-				+0.3
2,579,141	+				-0.6
2,579,161	+				-0.7
2,579,194	-				-0.1
2,579,194	-				+1.7
2,579,215	+				-0.5
2,579,278	+		Rv2307A	0.26	-0.1
2,579,298	+		Rv2307A	0.36	+1.7
2,579,457	-				-1.5
2,579,460	+				+0.1
2,579,580	+		Rv2307B	0.18	+0.6
2,579,581	+		Rv2307B	0.18	+0.2
2,579,609	+		Rv2307B	0.24	+0.2
2,579,662	-		Rv2307B	0.37	+0.5
2,579,717	-		Rv2307B	0.49	-0.2
2,580,110	+		Rv2307D	0.45	+0.9
2,580,111	-		Rv2307D	0.45	-0.4
2,580,150	+		Rv2307D	0.67	+0.3
2,580,263	+				+0.0
2,580,264	-				-0.1
2,580,269	+				-1.3
2,580,269	+				-1.7
2,580,269	+				-0.1
2,580,269	+				-0.5
2,580,270	-				+1.1
2,580,270	-				+0.7