Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0974c

Experiment: 7H9 with Rifampicin 0.014 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0973c and Rv0974c are separated by 5 nucleotidesRv0974c and Rv0975c are separated by 2 nucleotides Rv0973c: Rv0973c - Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrier protein (BCCP), at 1,083,747 to 1,085,750 Rv0973c Rv0974c: Rv0974c - Probable acetyl-/propionyl-CoA carboxylase (beta subunit) AccD2, at 1,085,756 to 1,087,345 Rv0974c Rv0975c: Rv0975c - Probable acyl-CoA dehydrogenase FadE13, at 1,087,348 to 1,088,496 Rv0975c Position (kb) 1085 1086 1087 1088Strain fitness (log2 ratio) -1 0 1 2at 1084.912 kb on + strand, within Rv0973cat 1086.102 kb on + strand, within Rv0974cat 1086.214 kb on - strand, within Rv0974cat 1087.466 kb on + strand, within Rv0975cat 1087.467 kb on - strand, within Rv0975cat 1087.604 kb on + strand, within Rv0975cat 1088.027 kb on + strand, within Rv0975cat 1088.027 kb on + strand, within Rv0975cat 1088.028 kb on - strand, within Rv0975cat 1088.083 kb on + strand, within Rv0975cat 1088.084 kb on - strand, within Rv0975cat 1088.240 kb on + strand, within Rv0975cat 1088.241 kb on - strand, within Rv0975cat 1088.241 kb on - strand, within Rv0975c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.014 ug/mL
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1,084,912 + Rv0973c 0.58 +0.8
1,086,102 + Rv0974c 0.22 -0.1
1,086,214 - Rv0974c 0.29 +0.6
1,087,466 + Rv0975c 0.10 -0.2
1,087,467 - Rv0975c 0.10 -0.2
1,087,604 + Rv0975c 0.22 -0.9
1,088,027 + Rv0975c 0.59 +0.7
1,088,027 + Rv0975c 0.59 +1.8
1,088,028 - Rv0975c 0.59 -0.8
1,088,083 + Rv0975c 0.64 +0.4
1,088,084 - Rv0975c 0.64 +0.5
1,088,240 + Rv0975c 0.78 -1.0
1,088,241 - Rv0975c 0.78 -0.3
1,088,241 - Rv0975c 0.78 -0.0

Or see this region's nucleotide sequence