Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0863

Experiment: 7H9 with Rifampicin 0.014 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0862c and Rv0863 overlap by 14 nucleotidesRv0863 and Rv0864 are separated by 9 nucleotidesRv0864 and Rv0865 overlap by 4 nucleotidesRv0865 and Rv0866 overlap by 4 nucleotides Rv0862c: Rv0862c - Conserved protein, at 960,342 to 962,612 Rv0862c Rv0863: Rv0863 - Conserved hypothetical protein, at 962,599 to 962,880 Rv0863 Rv0864: Rv0864 - Probable molybdenum cofactor biosynthesis protein C 2 MoaC2, at 962,890 to 963,393 Rv0864 Rv0865: Rv0865 - Probable molybdopterin biosynthesis Mog protein, at 963,390 to 963,872 Rv0865 Rv0866: Rv0866 - Probable molybdenum cofactor biosynthesis protein E2 MoaE2 (molybdopterin converting factor large subunit) (molybdopterin [MPT] converting factor, subunit 2), at 963,869 to 964,294 Rv0866 Position (kb) 962 963Strain fitness (log2 ratio) -2 -1 0 1 2at 961.729 kb on - strand, within Rv0862cat 962.700 kb on + strand, within Rv0863at 962.700 kb on + strand, within Rv0863at 962.719 kb on + strand, within Rv0863at 962.719 kb on + strand, within Rv0863at 962.848 kb on + strand, within Rv0863at 962.849 kb on - strand, within Rv0863at 962.849 kb on - strand, within Rv0863at 963.023 kb on + strand, within Rv0864at 963.023 kb on + strand, within Rv0864at 963.023 kb on + strand, within Rv0864at 963.023 kb on + strand, within Rv0864at 963.024 kb on - strand, within Rv0864at 963.028 kb on - strand, within Rv0864at 963.111 kb on + strand, within Rv0864at 963.111 kb on + strand, within Rv0864at 963.166 kb on - strand, within Rv0864at 963.295 kb on + strand, within Rv0864at 963.295 kb on + strand, within Rv0864at 963.449 kb on + strand, within Rv0865at 963.554 kb on - strand, within Rv0865at 963.657 kb on + strand, within Rv0865at 963.657 kb on + strand, within Rv0865at 963.793 kb on + strand, within Rv0865at 963.794 kb on - strand, within Rv0865at 963.794 kb on - strand, within Rv0865

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.014 ug/mL
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961,729 - Rv0862c 0.61 -0.7
962,700 + Rv0863 0.36 +0.4
962,700 + Rv0863 0.36 -1.2
962,719 + Rv0863 0.43 -0.0
962,719 + Rv0863 0.43 -1.1
962,848 + Rv0863 0.88 -0.6
962,849 - Rv0863 0.89 -1.2
962,849 - Rv0863 0.89 +0.2
963,023 + Rv0864 0.26 +0.3
963,023 + Rv0864 0.26 -0.4
963,023 + Rv0864 0.26 -1.5
963,023 + Rv0864 0.26 +0.3
963,024 - Rv0864 0.27 -0.3
963,028 - Rv0864 0.27 +0.5
963,111 + Rv0864 0.44 -0.4
963,111 + Rv0864 0.44 -0.4
963,166 - Rv0864 0.55 -1.4
963,295 + Rv0864 0.80 -0.9
963,295 + Rv0864 0.80 -1.9
963,449 + Rv0865 0.12 -1.0
963,554 - Rv0865 0.34 +0.5
963,657 + Rv0865 0.55 +0.1
963,657 + Rv0865 0.55 +1.0
963,793 + Rv0865 0.83 -2.0
963,794 - Rv0865 0.84 -1.3
963,794 - Rv0865 0.84 +1.8

Or see this region's nucleotide sequence