Experiment: 7H9 with Rifampicin 0.014 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0501 and Rv0502 are separated by 6 nucleotides Rv0502 and Rv0503c are separated by 3 nucleotides Rv0503c and Rv0504c are separated by 22 nucleotides
Rv0501: Rv0501 - Possible UDP-glucose 4-epimerase GalE2 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase), at 591,654 to 592,784
Rv0501
Rv0502: Rv0502 - Conserved protein, at 592,791 to 593,867
Rv0502
Rv0503c: Rv0503c - Cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic acid synthase 2) (mycolic acid trans-cyclopropane synthetase), at 593,871 to 594,779
Rv0503c
Rv0504c: Rv0504c - Conserved protein, at 594,802 to 595,302
Rv0504c
Position (kb)
592
593
594 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 591.884 kb on + strand, within Rv0501 at 591.960 kb on + strand, within Rv0501 at 592.001 kb on + strand, within Rv0501 at 592.001 kb on + strand, within Rv0501 at 592.192 kb on - strand, within Rv0501 at 592.235 kb on + strand, within Rv0501 at 592.290 kb on + strand, within Rv0501 at 592.573 kb on - strand, within Rv0501 at 592.617 kb on + strand, within Rv0501 at 592.618 kb on - strand, within Rv0501 at 593.089 kb on - strand, within Rv0502 at 593.137 kb on + strand, within Rv0502 at 593.384 kb on + strand, within Rv0502 at 593.384 kb on + strand, within Rv0502 at 593.385 kb on - strand, within Rv0502 at 593.396 kb on + strand, within Rv0502 at 593.397 kb on - strand, within Rv0502 at 593.457 kb on + strand, within Rv0502 at 593.458 kb on - strand, within Rv0502 at 593.524 kb on + strand, within Rv0502 at 593.590 kb on - strand, within Rv0502 at 593.590 kb on - strand, within Rv0502 at 593.652 kb on - strand, within Rv0502 at 593.745 kb on + strand, within Rv0502 at 593.824 kb on + strand at 593.824 kb on + strand at 593.825 kb on - strand at 593.825 kb on - strand at 593.873 kb on - strand at 593.873 kb on - strand at 593.873 kb on - strand at 593.905 kb on + strand at 593.906 kb on - strand at 593.906 kb on - strand at 593.906 kb on - strand at 593.906 kb on - strand at 593.937 kb on + strand at 593.937 kb on + strand at 593.937 kb on + strand at 593.937 kb on + strand at 593.938 kb on - strand at 593.938 kb on - strand at 593.938 kb on - strand at 593.938 kb on - strand at 593.938 kb on - strand at 593.941 kb on + strand at 593.942 kb on - strand at 593.942 kb on - strand at 593.950 kb on + strand at 593.950 kb on + strand at 593.950 kb on + strand at 593.951 kb on - strand at 593.951 kb on - strand at 593.951 kb on - strand at 593.959 kb on + strand at 593.959 kb on + strand at 593.960 kb on - strand at 594.040 kb on + strand, within Rv0503c at 594.040 kb on + strand, within Rv0503c at 594.040 kb on + strand, within Rv0503c at 594.040 kb on + strand, within Rv0503c at 594.041 kb on - strand, within Rv0503c at 594.041 kb on - strand, within Rv0503c at 594.094 kb on + strand, within Rv0503c at 594.094 kb on + strand, within Rv0503c at 594.094 kb on + strand, within Rv0503c at 594.094 kb on + strand, within Rv0503c at 594.094 kb on + strand, within Rv0503c at 594.095 kb on - strand, within Rv0503c at 594.095 kb on - strand, within Rv0503c at 594.095 kb on - strand, within Rv0503c at 594.097 kb on + strand, within Rv0503c at 594.097 kb on + strand, within Rv0503c at 594.097 kb on + strand, within Rv0503c at 594.097 kb on + strand, within Rv0503c at 594.098 kb on - strand, within Rv0503c at 594.098 kb on - strand, within Rv0503c at 594.098 kb on - strand, within Rv0503c at 594.098 kb on - strand, within Rv0503c at 594.271 kb on + strand, within Rv0503c at 594.272 kb on - strand, within Rv0503c at 594.457 kb on + strand, within Rv0503c at 594.457 kb on + strand, within Rv0503c at 594.499 kb on + strand, within Rv0503c at 594.500 kb on - strand, within Rv0503c at 594.607 kb on + strand, within Rv0503c at 594.608 kb on - strand, within Rv0503c at 594.629 kb on + strand, within Rv0503c at 594.629 kb on + strand, within Rv0503c at 594.630 kb on - strand, within Rv0503c at 594.630 kb on - strand, within Rv0503c at 594.647 kb on - strand, within Rv0503c at 594.658 kb on + strand, within Rv0503c at 594.658 kb on + strand, within Rv0503c at 594.658 kb on + strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.791 kb on + strand at 594.791 kb on + strand at 594.792 kb on - strand at 594.804 kb on - strand at 594.804 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.014 ug/mL remove 591,884 + Rv0501 0.20 -2.7 591,960 + Rv0501 0.27 +0.8 592,001 + Rv0501 0.31 -0.2 592,001 + Rv0501 0.31 +0.6 592,192 - Rv0501 0.48 -0.4 592,235 + Rv0501 0.51 -0.1 592,290 + Rv0501 0.56 -0.2 592,573 - Rv0501 0.81 +1.7 592,617 + Rv0501 0.85 +0.4 592,618 - Rv0501 0.85 +0.6 593,089 - Rv0502 0.28 -0.1 593,137 + Rv0502 0.32 -0.7 593,384 + Rv0502 0.55 -1.4 593,384 + Rv0502 0.55 -0.1 593,385 - Rv0502 0.55 +1.4 593,396 + Rv0502 0.56 -0.3 593,397 - Rv0502 0.56 +0.1 593,457 + Rv0502 0.62 -0.3 593,458 - Rv0502 0.62 +0.5 593,524 + Rv0502 0.68 -0.1 593,590 - Rv0502 0.74 +0.6 593,590 - Rv0502 0.74 -0.1 593,652 - Rv0502 0.80 +0.2 593,745 + Rv0502 0.89 -0.1 593,824 + +1.3 593,824 + -1.0 593,825 - +0.2 593,825 - +0.0 593,873 - +0.1 593,873 - +0.8 593,873 - +0.2 593,905 + -0.4 593,906 - +0.0 593,906 - +1.0 593,906 - -1.2 593,906 - +1.8 593,937 + -0.8 593,937 + -0.8 593,937 + -0.4 593,937 + +1.5 593,938 - +0.0 593,938 - -0.1 593,938 - -1.9 593,938 - -0.7 593,938 - -1.2 593,941 + -0.5 593,942 - -0.6 593,942 - -0.6 593,950 + -0.6 593,950 + -0.6 593,950 + -0.7 593,951 - -0.6 593,951 - -0.3 593,951 - -0.5 593,959 + -0.7 593,959 + -2.3 593,960 - +1.1 594,040 + Rv0503c 0.19 -0.6 594,040 + Rv0503c 0.19 -0.7 594,040 + Rv0503c 0.19 -0.2 594,040 + Rv0503c 0.19 -1.0 594,041 - Rv0503c 0.19 -0.2 594,041 - Rv0503c 0.19 -0.8 594,094 + Rv0503c 0.25 -1.4 594,094 + Rv0503c 0.25 -0.9 594,094 + Rv0503c 0.25 -1.0 594,094 + Rv0503c 0.25 +0.1 594,094 + Rv0503c 0.25 -0.5 594,095 - Rv0503c 0.25 -0.9 594,095 - Rv0503c 0.25 -1.5 594,095 - Rv0503c 0.25 -2.2 594,097 + Rv0503c 0.25 -0.6 594,097 + Rv0503c 0.25 -1.0 594,097 + Rv0503c 0.25 -0.8 594,097 + Rv0503c 0.25 -1.0 594,098 - Rv0503c 0.25 -0.3 594,098 - Rv0503c 0.25 -1.0 594,098 - Rv0503c 0.25 +0.2 594,098 - Rv0503c 0.25 -0.5 594,271 + Rv0503c 0.44 -0.8 594,272 - Rv0503c 0.44 -0.8 594,457 + Rv0503c 0.64 -0.8 594,457 + Rv0503c 0.64 -0.2 594,499 + Rv0503c 0.69 +1.8 594,500 - Rv0503c 0.69 -0.3 594,607 + Rv0503c 0.81 -0.7 594,608 - Rv0503c 0.81 -0.6 594,629 + Rv0503c 0.83 -0.8 594,629 + Rv0503c 0.83 +0.3 594,630 - Rv0503c 0.83 -0.4 594,630 - Rv0503c 0.83 -0.6 594,647 - Rv0503c 0.85 -0.5 594,658 + Rv0503c 0.87 -0.3 594,658 + Rv0503c 0.87 -0.2 594,658 + Rv0503c 0.87 -0.6 594,659 - Rv0503c 0.87 -0.2 594,659 - Rv0503c 0.87 -1.0 594,659 - Rv0503c 0.87 +0.5 594,659 - Rv0503c 0.87 -2.5 594,659 - Rv0503c 0.87 -0.8 594,791 + -0.4 594,791 + -0.6 594,792 - +0.4 594,804 - -1.0 594,804 - +0.0
Or see this region's nucleotide sequence