Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3549c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3548c and Rv3549c are separated by 22 nucleotidesRv3549c and Rv3550 are separated by 54 nucleotidesRv3550 and Rv3551 overlap by 1 nucleotides Rv3548c: Rv3548c - Probable short-chain type dehydrogenase/reductase, at 3,987,382 to 3,988,296 Rv3548c Rv3549c: Rv3549c - Probable short-chain type dehydrogenase/reductase, at 3,988,319 to 3,989,098 Rv3549c Rv3550: Rv3550 - Probable enoyl-CoA hydratase EchA20 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 3,989,153 to 3,989,896 Rv3550 Rv3551: Rv3551 - Possible CoA-transferase (alpha subunit), at 3,989,896 to 3,990,774 Rv3551 Position (kb) 3988 3989 3990Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3987.380 kb on - strandat 3987.383 kb on + strandat 3987.392 kb on + strandat 3987.393 kb on - strandat 3987.539 kb on - strand, within Rv3548cat 3987.580 kb on + strand, within Rv3548cat 3987.581 kb on - strand, within Rv3548cat 3987.776 kb on + strand, within Rv3548cat 3987.777 kb on - strand, within Rv3548cat 3987.802 kb on + strand, within Rv3548cat 3987.803 kb on - strand, within Rv3548cat 3987.803 kb on - strand, within Rv3548cat 3987.803 kb on - strand, within Rv3548cat 3987.803 kb on - strand, within Rv3548cat 3988.026 kb on - strand, within Rv3548cat 3988.026 kb on - strand, within Rv3548cat 3988.348 kb on - strandat 3988.636 kb on - strand, within Rv3549cat 3988.815 kb on + strand, within Rv3549cat 3988.932 kb on + strand, within Rv3549cat 3989.423 kb on + strand, within Rv3550at 3989.424 kb on - strand, within Rv3550at 3989.811 kb on - strand, within Rv3550at 3989.831 kb on - strandat 3989.894 kb on + strandat 3989.894 kb on + strandat 3989.894 kb on + strandat 3989.894 kb on + strandat 3989.895 kb on - strandat 3990.049 kb on + strand, within Rv3551

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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3,987,380 - +2.9
3,987,383 + +0.9
3,987,392 + +0.8
3,987,393 - -0.3
3,987,539 - Rv3548c 0.17 -0.4
3,987,580 + Rv3548c 0.22 -0.6
3,987,581 - Rv3548c 0.22 +0.2
3,987,776 + Rv3548c 0.43 -0.4
3,987,777 - Rv3548c 0.43 +0.1
3,987,802 + Rv3548c 0.46 -1.6
3,987,803 - Rv3548c 0.46 -1.0
3,987,803 - Rv3548c 0.46 -0.4
3,987,803 - Rv3548c 0.46 -0.7
3,987,803 - Rv3548c 0.46 -0.0
3,988,026 - Rv3548c 0.70 -0.0
3,988,026 - Rv3548c 0.70 -0.6
3,988,348 - -1.0
3,988,636 - Rv3549c 0.41 -0.1
3,988,815 + Rv3549c 0.64 +0.2
3,988,932 + Rv3549c 0.79 +0.7
3,989,423 + Rv3550 0.36 +0.2
3,989,424 - Rv3550 0.36 +0.1
3,989,811 - Rv3550 0.88 +0.1
3,989,831 - +0.2
3,989,894 + -0.5
3,989,894 + -0.3
3,989,894 + -0.6
3,989,894 + -0.3
3,989,895 - -1.8
3,990,049 + Rv3551 0.17 -0.7

Or see this region's nucleotide sequence