Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3395c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3394c and Rv3395c overlap by 4 nucleotidesRv3395c and Rv3395A are separated by 82 nucleotidesRv3395A and Rv3396c are separated by 155 nucleotides Rv3394c: Rv3394c - Conserved hypothetical protein, at 3,809,442 to 3,811,025 Rv3394c Rv3395c: Rv3395c - Conserved hypothetical protein, at 3,811,022 to 3,811,636 Rv3395c Rv3395A: Rv3395A - Probable membrane protein, at 3,811,719 to 3,812,345 Rv3395A Rv3396c: Rv3396c - Probable GMP synthase [glutamine-hydrolyzing] GuaA (glutamine amidotransferase) (GMP synthetase), at 3,812,501 to 3,814,078 Rv3396c Position (kb) 3811 3812Strain fitness (log2 ratio) -1 0 1 2at 3810.818 kb on + strand, within Rv3394cat 3810.818 kb on + strand, within Rv3394cat 3810.989 kb on + strandat 3810.990 kb on - strandat 3811.113 kb on + strand, within Rv3395cat 3811.730 kb on + strandat 3811.730 kb on + strandat 3811.730 kb on + strandat 3811.777 kb on + strandat 3812.082 kb on + strand, within Rv3395Aat 3812.083 kb on - strand, within Rv3395Aat 3812.083 kb on - strand, within Rv3395Aat 3812.083 kb on - strand, within Rv3395Aat 3812.230 kb on + strand, within Rv3395Aat 3812.343 kb on + strandat 3812.343 kb on + strandat 3812.344 kb on - strandat 3812.392 kb on + strandat 3812.392 kb on + strandat 3812.433 kb on + strandat 3812.434 kb on - strandat 3812.449 kb on + strandat 3812.449 kb on + strandat 3812.449 kb on + strandat 3812.449 kb on + strandat 3812.449 kb on + strandat 3812.450 kb on - strandat 3812.450 kb on - strandat 3812.486 kb on + strandat 3812.502 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
remove
3,810,818 + Rv3394c 0.87 -0.4
3,810,818 + Rv3394c 0.87 +0.3
3,810,989 + -0.1
3,810,990 - +0.3
3,811,113 + Rv3395c 0.15 +0.2
3,811,730 + -0.6
3,811,730 + -0.4
3,811,730 + +1.0
3,811,777 + -0.1
3,812,082 + Rv3395A 0.58 +0.3
3,812,083 - Rv3395A 0.58 -0.3
3,812,083 - Rv3395A 0.58 -0.3
3,812,083 - Rv3395A 0.58 -0.7
3,812,230 + Rv3395A 0.81 +0.6
3,812,343 + +2.5
3,812,343 + -0.5
3,812,344 - -0.5
3,812,392 + +0.1
3,812,392 + +0.3
3,812,433 + +0.7
3,812,434 - -1.0
3,812,449 + +0.5
3,812,449 + -1.5
3,812,449 + -0.4
3,812,449 + +0.0
3,812,449 + +0.2
3,812,450 - -0.6
3,812,450 - -0.8
3,812,486 + +0.9
3,812,502 + -1.2

Or see this region's nucleotide sequence