Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3312A

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3312c and Rv3312A are separated by 374 nucleotidesRv3312A and Rv3313c are separated by 70 nucleotides Rv3312c: Rv3312c - Conserved hypothetical protein, at 3,699,404 to 3,700,330 Rv3312c Rv3312A: Rv3312A - Secreted protein antigen, at 3,700,705 to 3,701,016 Rv3312A Rv3313c: Rv3313c - Probable adenosine deaminase Add (adenosine aminohydrolase), at 3,701,087 to 3,702,184 Rv3313c Position (kb) 3700 3701 3702Strain fitness (log2 ratio) -2 -1 0 1at 3699.766 kb on + strand, within Rv3312cat 3699.766 kb on + strand, within Rv3312cat 3699.858 kb on + strand, within Rv3312cat 3699.859 kb on - strand, within Rv3312cat 3700.104 kb on + strand, within Rv3312cat 3700.125 kb on - strand, within Rv3312cat 3700.203 kb on + strand, within Rv3312cat 3700.204 kb on - strand, within Rv3312cat 3700.243 kb on - strandat 3700.348 kb on + strandat 3700.349 kb on - strandat 3700.349 kb on - strandat 3700.413 kb on - strandat 3700.413 kb on - strandat 3700.575 kb on + strandat 3700.641 kb on + strandat 3700.668 kb on - strandat 3700.669 kb on + strandat 3700.675 kb on + strandat 3700.707 kb on - strandat 3700.844 kb on + strand, within Rv3312Aat 3700.844 kb on + strand, within Rv3312Aat 3700.845 kb on - strand, within Rv3312Aat 3700.845 kb on - strand, within Rv3312Aat 3700.898 kb on + strand, within Rv3312Aat 3700.898 kb on + strand, within Rv3312Aat 3700.901 kb on + strand, within Rv3312Aat 3700.901 kb on + strand, within Rv3312Aat 3700.902 kb on - strand, within Rv3312Aat 3701.013 kb on - strandat 3701.059 kb on - strandat 3701.070 kb on - strandat 3701.234 kb on + strand, within Rv3313cat 3701.324 kb on + strand, within Rv3313cat 3701.419 kb on + strand, within Rv3313cat 3701.419 kb on + strand, within Rv3313cat 3701.881 kb on - strand, within Rv3313cat 3701.932 kb on - strand, within Rv3313cat 3701.985 kb on + strand, within Rv3313c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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3,699,766 + Rv3312c 0.39 -0.1
3,699,766 + Rv3312c 0.39 -0.3
3,699,858 + Rv3312c 0.49 -0.3
3,699,859 - Rv3312c 0.49 -0.9
3,700,104 + Rv3312c 0.76 +0.7
3,700,125 - Rv3312c 0.78 +0.0
3,700,203 + Rv3312c 0.86 -2.1
3,700,204 - Rv3312c 0.86 -0.1
3,700,243 - -0.5
3,700,348 + -1.1
3,700,349 - +0.7
3,700,349 - -0.2
3,700,413 - +0.7
3,700,413 - -1.8
3,700,575 + -0.9
3,700,641 + -1.4
3,700,668 - -0.3
3,700,669 + -0.4
3,700,675 + -0.5
3,700,707 - -1.0
3,700,844 + Rv3312A 0.45 -0.1
3,700,844 + Rv3312A 0.45 -0.1
3,700,845 - Rv3312A 0.45 +1.2
3,700,845 - Rv3312A 0.45 +0.6
3,700,898 + Rv3312A 0.62 -0.3
3,700,898 + Rv3312A 0.62 +0.5
3,700,901 + Rv3312A 0.63 +0.2
3,700,901 + Rv3312A 0.63 +1.7
3,700,902 - Rv3312A 0.63 +0.0
3,701,013 - +1.5
3,701,059 - +0.3
3,701,070 - +0.2
3,701,234 + Rv3313c 0.13 -0.3
3,701,324 + Rv3313c 0.22 -0.7
3,701,419 + Rv3313c 0.30 -0.2
3,701,419 + Rv3313c 0.30 -0.3
3,701,881 - Rv3313c 0.72 -0.4
3,701,932 - Rv3313c 0.77 +0.3
3,701,985 + Rv3313c 0.82 -0.5

Or see this region's nucleotide sequence