Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2938

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Rifampicin 0.00045 ug/mL
3,273,103	+		Rv2936	0.89	+0.2
3,273,103	+		Rv2936	0.89	-1.6
3,273,110	+				-1.5
3,273,143	-				-0.9
3,273,222	+				-0.3
3,273,223	-				+0.2
3,273,223	-				-0.8
3,273,223	-				-1.7
3,273,351	+		Rv2937	0.17	-2.4
3,273,351	+		Rv2937	0.17	-0.8
3,273,351	+		Rv2937	0.17	-1.9
3,273,351	+		Rv2937	0.17	-1.2
3,273,352	-		Rv2937	0.17	+0.4
3,273,352	-		Rv2937	0.17	-1.1
3,273,395	+		Rv2937	0.22	-2.4
3,273,395	+		Rv2937	0.22	-1.2
3,273,395	+		Rv2937	0.22	-2.0
3,273,396	-		Rv2937	0.22	-0.4
3,273,396	-		Rv2937	0.22	-1.7
3,273,396	-		Rv2937	0.22	-1.7
3,273,396	-		Rv2937	0.22	-1.2
3,273,396	-		Rv2937	0.22	+0.6
3,273,398	-		Rv2937	0.22	-1.5
3,273,412	-		Rv2937	0.24	-2.3
3,273,462	+		Rv2937	0.29	-1.4
3,273,470	+		Rv2937	0.30	-1.5
3,273,470	+		Rv2937	0.30	-2.1
3,273,470	+		Rv2937	0.30	-1.7
3,273,471	-		Rv2937	0.30	-0.6
3,273,471	-		Rv2937	0.30	-1.5
3,273,471	-		Rv2937	0.30	-1.0
3,273,471	-		Rv2937	0.30	-1.2
3,273,471	-		Rv2937	0.30	-0.9
3,273,661	-		Rv2937	0.52	-1.4
3,273,672	-		Rv2937	0.54	-1.1
3,273,707	+		Rv2937	0.58	-1.4
3,273,955	+		Rv2937	0.86	-2.7
3,273,955	+		Rv2937	0.86	+0.1
3,273,956	-		Rv2937	0.86	-1.4
3,274,184	+		Rv2938	0.13	-1.7
3,274,185	-		Rv2938	0.14	-0.6
3,274,204	+		Rv2938	0.16	-1.8
3,274,205	-		Rv2938	0.16	-1.3
3,274,206	+		Rv2938	0.16	-2.1
3,274,206	+		Rv2938	0.16	-2.7
3,274,207	-		Rv2938	0.16	-0.3
3,274,269	-		Rv2938	0.24	-1.0
3,274,269	-		Rv2938	0.24	-1.8
3,274,269	-		Rv2938	0.24	-2.4
3,274,272	+		Rv2938	0.24	-1.2
3,274,277	+		Rv2938	0.25	-1.8
3,274,277	+		Rv2938	0.25	-2.2
3,274,277	+		Rv2938	0.25	-2.4
3,274,277	+		Rv2938	0.25	-1.2
3,274,277	+		Rv2938	0.25	-1.6
3,274,278	-		Rv2938	0.25	-1.2
3,274,278	-		Rv2938	0.25	-1.0
3,274,282	+		Rv2938	0.25	-1.9
3,274,282	+		Rv2938	0.25	+1.8
3,274,283	-		Rv2938	0.25	-2.2
3,274,283	-		Rv2938	0.25	-1.0
3,274,283	-		Rv2938	0.25	-0.6
3,274,309	+		Rv2938	0.29	-1.4
3,274,310	-		Rv2938	0.29	-1.9
3,274,494	-		Rv2938	0.51	-0.5
3,274,502	+		Rv2938	0.52	+0.0
3,274,502	+		Rv2938	0.52	-0.5
3,274,502	+		Rv2938	0.52	-1.0
3,274,503	-		Rv2938	0.52	-1.6
3,274,503	-		Rv2938	0.52	+0.2
3,274,507	-		Rv2938	0.52	-1.1
3,274,517	+		Rv2938	0.54	-1.9
3,274,567	-		Rv2938	0.60	-1.3
3,274,567	-		Rv2938	0.60	-1.5
3,274,611	+		Rv2938	0.65	-3.0
3,274,611	+		Rv2938	0.65	-1.5
3,274,759	+		Rv2938	0.83	-1.1
3,274,759	+		Rv2938	0.83	+1.8
3,274,760	-		Rv2938	0.83	+0.5
3,274,853	+				-1.4
3,274,854	-				-0.5
3,275,018	-				+0.4
3,275,259	+		Rv2939	0.24	+0.5
3,275,307	+		Rv2939	0.28	-0.0
3,275,307	+		Rv2939	0.28	+0.5
3,275,309	+		Rv2939	0.28	+1.8
3,275,309	+		Rv2939	0.28	+1.7
3,275,309	+		Rv2939	0.28	+1.6
3,275,309	+		Rv2939	0.28	+0.8
3,275,309	+		Rv2939	0.28	+0.4
3,275,309	+		Rv2939	0.28	+0.7
3,275,310	-		Rv2939	0.28	-0.6
3,275,310	-		Rv2939	0.28	+0.4
3,275,310	-		Rv2939	0.28	+0.5
3,275,500	+		Rv2939	0.43	-0.9
3,275,501	-		Rv2939	0.43	+0.4
3,275,501	-		Rv2939	0.43	+0.5
3,275,513	+		Rv2939	0.44	+0.6
3,275,513	+		Rv2939	0.44	+0.7
3,275,513	+		Rv2939	0.44	+0.9
3,275,513	+		Rv2939	0.44	+0.2
3,275,513	+		Rv2939	0.44	+0.5
3,275,513	+		Rv2939	0.44	+0.5
3,275,513	+		Rv2939	0.44	+1.2
3,275,513	+		Rv2939	0.44	+0.3
3,275,513	+		Rv2939	0.44	+1.1
3,275,513	+		Rv2939	0.44	+0.7
3,275,514	-		Rv2939	0.45	+0.9
3,275,514	-		Rv2939	0.45	+1.4
3,275,514	-		Rv2939	0.45	+0.4
3,275,520	-		Rv2939	0.45	+0.4
3,275,520	-		Rv2939	0.45	+0.8
3,275,738	+		Rv2939	0.62	+1.1
3,275,764	-		Rv2939	0.64	+0.7
3,275,791	+		Rv2939	0.66	+0.3
3,275,791	+		Rv2939	0.66	+0.7
3,275,792	-		Rv2939	0.66	+0.4
3,275,792	-		Rv2939	0.66	+0.3
3,275,839	+		Rv2939	0.70	+0.3