Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2851c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2850c and Rv2851c overlap by 4 nucleotidesRv2851c and Rv2852c are separated by 58 nucleotides Rv2850c: Rv2850c - Possible magnesium chelatase, at 3,158,165 to 3,160,054 Rv2850c Rv2851c: Rv2851c - GCN5-related N-acetyltransferase, at 3,160,051 to 3,160,521 Rv2851c Rv2852c: Rv2852c - Probable malate:quinone oxidoreductase Mqo (malate dehydrogenase [acceptor]), at 3,160,580 to 3,162,061 Rv2852c Position (kb) 3160 3161Strain fitness (log2 ratio) -1 0 1 2at 3159.665 kb on + strand, within Rv2850cat 3159.666 kb on - strand, within Rv2850cat 3160.154 kb on + strand, within Rv2851cat 3160.154 kb on + strand, within Rv2851cat 3160.169 kb on + strand, within Rv2851cat 3160.169 kb on + strand, within Rv2851cat 3160.267 kb on - strand, within Rv2851cat 3160.402 kb on + strand, within Rv2851cat 3160.522 kb on - strandat 3160.562 kb on + strandat 3160.563 kb on - strandat 3160.593 kb on - strandat 3160.795 kb on + strand, within Rv2852cat 3160.986 kb on + strand, within Rv2852cat 3161.205 kb on - strand, within Rv2852cat 3161.205 kb on - strand, within Rv2852cat 3161.205 kb on - strand, within Rv2852c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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3,159,665 + Rv2850c 0.79 +0.3
3,159,666 - Rv2850c 0.79 -0.1
3,160,154 + Rv2851c 0.22 -1.0
3,160,154 + Rv2851c 0.22 -0.1
3,160,169 + Rv2851c 0.25 -0.5
3,160,169 + Rv2851c 0.25 -0.7
3,160,267 - Rv2851c 0.46 -0.4
3,160,402 + Rv2851c 0.75 -0.7
3,160,522 - +0.7
3,160,562 + -0.7
3,160,563 - +1.4
3,160,593 - -0.8
3,160,795 + Rv2852c 0.15 -1.0
3,160,986 + Rv2852c 0.27 -1.0
3,161,205 - Rv2852c 0.42 +0.4
3,161,205 - Rv2852c 0.42 +0.3
3,161,205 - Rv2852c 0.42 +1.8

Or see this region's nucleotide sequence