Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2774c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2772c and Rv2773c are separated by 11 nucleotidesRv2773c and Rv2774c are separated by 10 nucleotidesRv2774c and Rv2775 are separated by 152 nucleotidesRv2775 and Rv2776c are separated by 3 nucleotides Rv2772c: Rv2772c - Probable conserved transmembrane protein, at 3,081,119 to 3,081,592 Rv2772c Rv2773c: Rv2773c - Dihydrodipicolinate reductase DapB (DHPR), at 3,081,604 to 3,082,341 Rv2773c Rv2774c: Rv2774c - Hypothetical protein, at 3,082,352 to 3,082,756 Rv2774c Rv2775: Rv2775 - GCN5-related N-acetyltransferase, at 3,082,909 to 3,083,370 Rv2775 Rv2776c: Rv2776c - Probable oxidoreductase, at 3,083,374 to 3,084,303 Rv2776c Position (kb) 3082 3083Strain fitness (log2 ratio) -2 -1 0 1at 3081.388 kb on - strand, within Rv2772cat 3081.528 kb on + strand, within Rv2772cat 3081.573 kb on + strandat 3081.573 kb on + strandat 3081.574 kb on - strandat 3082.454 kb on - strand, within Rv2774cat 3082.454 kb on - strand, within Rv2774cat 3082.800 kb on + strandat 3082.801 kb on - strandat 3082.804 kb on + strandat 3082.805 kb on - strandat 3082.805 kb on - strandat 3082.861 kb on - strandat 3082.961 kb on + strand, within Rv2775at 3083.037 kb on + strand, within Rv2775at 3083.038 kb on - strand, within Rv2775at 3083.131 kb on + strand, within Rv2775at 3083.131 kb on + strand, within Rv2775at 3083.132 kb on - strand, within Rv2775at 3083.132 kb on - strand, within Rv2775at 3083.257 kb on + strand, within Rv2775at 3083.347 kb on + strandat 3083.660 kb on + strand, within Rv2776cat 3083.710 kb on + strand, within Rv2776cat 3083.711 kb on - strand, within Rv2776cat 3083.735 kb on + strand, within Rv2776cat 3083.736 kb on - strand, within Rv2776c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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3,081,388 - Rv2772c 0.57 +0.6
3,081,528 + Rv2772c 0.86 -0.3
3,081,573 + +0.7
3,081,573 + -0.1
3,081,574 - -1.2
3,082,454 - Rv2774c 0.25 -0.5
3,082,454 - Rv2774c 0.25 +0.8
3,082,800 + +0.7
3,082,801 - -0.7
3,082,804 + -0.4
3,082,805 - +1.1
3,082,805 - -0.3
3,082,861 - -1.0
3,082,961 + Rv2775 0.11 -0.6
3,083,037 + Rv2775 0.28 -0.7
3,083,038 - Rv2775 0.28 +0.0
3,083,131 + Rv2775 0.48 -0.8
3,083,131 + Rv2775 0.48 +0.7
3,083,132 - Rv2775 0.48 -0.3
3,083,132 - Rv2775 0.48 +0.1
3,083,257 + Rv2775 0.75 -0.2
3,083,347 + -0.0
3,083,660 + Rv2776c 0.31 +0.0
3,083,710 + Rv2776c 0.36 -0.1
3,083,711 - Rv2776c 0.36 +1.0
3,083,735 + Rv2776c 0.39 -2.6
3,083,736 - Rv2776c 0.39 -0.1

Or see this region's nucleotide sequence