Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2478c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2477c and Rv2478c are separated by 80 nucleotidesRv2478c and Rv2479c are separated by 48 nucleotides Rv2477c: Rv2477c - Probable macrolide-transport ATP-binding protein ABC transporter, at 2,782,366 to 2,784,042 Rv2477c Rv2478c: Rv2478c - Conserved hypothetical protein, at 2,784,123 to 2,784,608 Rv2478c Rv2479c: Rv2479c - Probable transposase, at 2,784,657 to 2,785,643 Rv2479c Rv2480c: Rv2480c - Possible transposase for insertion sequence element IS6110 (fragment), at 2,785,592 to 2,785,918 Rv2480c Position (kb) 2784 2785Strain fitness (log2 ratio) -1 0 1 2at 2784.091 kb on + strandat 2784.091 kb on + strandat 2784.092 kb on - strandat 2784.092 kb on - strandat 2784.092 kb on - strandat 2784.125 kb on - strandat 2784.274 kb on + strand, within Rv2478cat 2784.388 kb on + strand, within Rv2478cat 2784.388 kb on + strand, within Rv2478cat 2784.476 kb on + strand, within Rv2478c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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2,784,091 + +0.5
2,784,091 + +0.1
2,784,092 - -1.0
2,784,092 - -0.6
2,784,092 - +0.4
2,784,125 - -0.3
2,784,274 + Rv2478c 0.31 +1.8
2,784,388 + Rv2478c 0.55 -0.1
2,784,388 + Rv2478c 0.55 -0.1
2,784,476 + Rv2478c 0.73 +0.7

Or see this region's nucleotide sequence