Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2416c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2415c and Rv2416c are separated by 339 nucleotidesRv2416c and Rv2417c are separated by 139 nucleotides Rv2415c: Rv2415c - Conserved hypothetical protein, at 2,712,891 to 2,713,784 Rv2415c Rv2416c: Rv2416c - Enhanced intracellular survival protein Eis,GCN5-related N-acetyltransferase, at 2,714,124 to 2,715,332 Rv2416c Rv2417c: Rv2417c - Conserved protein, at 2,715,472 to 2,716,314 Rv2417c Position (kb) 2714 2715 2716Strain fitness (log2 ratio) -1 0 1 2at 2713.500 kb on + strand, within Rv2415cat 2713.699 kb on - strandat 2714.405 kb on - strand, within Rv2416cat 2714.471 kb on + strand, within Rv2416cat 2714.472 kb on - strand, within Rv2416cat 2714.666 kb on - strand, within Rv2416cat 2714.859 kb on + strand, within Rv2416cat 2715.314 kb on + strandat 2715.375 kb on + strandat 2715.376 kb on - strandat 2715.473 kb on + strandat 2715.473 kb on + strandat 2715.906 kb on + strand, within Rv2417cat 2716.228 kb on - strand, within Rv2417cat 2716.291 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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2,713,500 + Rv2415c 0.68 -0.3
2,713,699 - -0.1
2,714,405 - Rv2416c 0.23 -0.1
2,714,471 + Rv2416c 0.29 +1.8
2,714,472 - Rv2416c 0.29 +0.2
2,714,666 - Rv2416c 0.45 +0.0
2,714,859 + Rv2416c 0.61 +0.8
2,715,314 + -0.3
2,715,375 + +0.0
2,715,376 - -0.2
2,715,473 + +1.2
2,715,473 + -0.5
2,715,906 + Rv2417c 0.51 +0.1
2,716,228 - Rv2417c 0.90 -0.3
2,716,291 - +0.0

Or see this region's nucleotide sequence