Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0822c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0820 and Rv0821c are separated by 55 nucleotidesRv0821c and Rv0822c are separated by 57 nucleotidesRv0822c and Rv0823c are separated by 165 nucleotides Rv0820: Rv0820 - Probable phosphate-transport ATP-binding protein ABC transporter PhoT, at 912,726 to 913,502 Rv0820 Rv0821c: Rv0821c - Probable phosphate-transport system transcriptional regulatory protein PhoY2, at 913,558 to 914,199 Rv0821c Rv0822c: Rv0822c - Conserved protein, at 914,257 to 916,311 Rv0822c Rv0823c: Rv0823c - Possible transcriptional regulatory protein, at 916,477 to 917,646 Rv0823c Position (kb) 914 915 916 917Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2at 913.317 kb on + strand, within Rv0820at 913.317 kb on + strand, within Rv0820at 913.318 kb on - strand, within Rv0820at 913.340 kb on + strand, within Rv0820at 913.341 kb on - strand, within Rv0820at 913.420 kb on + strand, within Rv0820at 913.421 kb on - strand, within Rv0820at 913.500 kb on + strandat 913.631 kb on + strand, within Rv0821cat 913.632 kb on - strand, within Rv0821cat 913.632 kb on - strand, within Rv0821cat 913.842 kb on - strand, within Rv0821cat 914.135 kb on - strandat 914.186 kb on + strandat 914.186 kb on + strandat 914.205 kb on - strandat 914.211 kb on + strandat 914.212 kb on - strandat 914.338 kb on + strandat 914.339 kb on - strandat 914.622 kb on + strand, within Rv0822cat 914.622 kb on + strand, within Rv0822cat 914.622 kb on + strand, within Rv0822cat 914.623 kb on - strand, within Rv0822cat 914.829 kb on + strand, within Rv0822cat 914.860 kb on + strand, within Rv0822cat 914.861 kb on - strand, within Rv0822cat 914.861 kb on - strand, within Rv0822cat 914.862 kb on + strand, within Rv0822cat 914.904 kb on + strand, within Rv0822cat 914.904 kb on + strand, within Rv0822cat 914.960 kb on + strand, within Rv0822cat 914.960 kb on + strand, within Rv0822cat 914.961 kb on - strand, within Rv0822cat 914.961 kb on - strand, within Rv0822cat 914.961 kb on - strand, within Rv0822cat 915.125 kb on + strand, within Rv0822cat 915.125 kb on + strand, within Rv0822cat 915.125 kb on + strand, within Rv0822cat 915.125 kb on + strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.192 kb on - strand, within Rv0822cat 915.192 kb on - strand, within Rv0822cat 915.217 kb on + strand, within Rv0822cat 915.217 kb on + strand, within Rv0822cat 915.218 kb on - strand, within Rv0822cat 915.323 kb on - strand, within Rv0822cat 915.323 kb on - strand, within Rv0822cat 915.330 kb on + strand, within Rv0822cat 915.331 kb on - strand, within Rv0822cat 915.331 kb on - strand, within Rv0822cat 915.374 kb on + strand, within Rv0822cat 915.425 kb on + strand, within Rv0822cat 915.425 kb on + strand, within Rv0822cat 915.426 kb on - strand, within Rv0822cat 915.426 kb on - strand, within Rv0822cat 915.426 kb on - strand, within Rv0822cat 915.426 kb on - strand, within Rv0822cat 915.426 kb on - strand, within Rv0822cat 915.426 kb on - strand, within Rv0822cat 915.429 kb on + strand, within Rv0822cat 915.697 kb on + strand, within Rv0822cat 915.697 kb on + strand, within Rv0822cat 915.698 kb on - strand, within Rv0822cat 915.947 kb on + strand, within Rv0822cat 915.948 kb on - strand, within Rv0822cat 915.948 kb on - strand, within Rv0822cat 916.153 kb on - strandat 916.316 kb on + strandat 916.316 kb on + strandat 916.334 kb on + strandat 916.335 kb on - strandat 916.335 kb on - strandat 916.719 kb on - strand, within Rv0823cat 916.876 kb on + strand, within Rv0823cat 916.876 kb on + strand, within Rv0823cat 916.964 kb on + strand, within Rv0823cat 916.964 kb on + strand, within Rv0823cat 916.964 kb on + strand, within Rv0823cat 916.964 kb on + strand, within Rv0823cat 916.965 kb on - strand, within Rv0823cat 916.965 kb on - strand, within Rv0823cat 916.965 kb on - strand, within Rv0823cat 916.965 kb on - strand, within Rv0823cat 916.965 kb on - strand, within Rv0823cat 917.049 kb on - strand, within Rv0823cat 917.049 kb on - strand, within Rv0823cat 917.064 kb on + strand, within Rv0823cat 917.177 kb on - strand, within Rv0823cat 917.178 kb on + strand, within Rv0823cat 917.179 kb on - strand, within Rv0823cat 917.179 kb on - strand, within Rv0823cat 917.228 kb on - strand, within Rv0823c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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913,317 + Rv0820 0.76 -1.7
913,317 + Rv0820 0.76 -0.6
913,318 - Rv0820 0.76 -0.1
913,340 + Rv0820 0.79 -3.4
913,341 - Rv0820 0.79 -3.8
913,420 + Rv0820 0.89 -3.2
913,421 - Rv0820 0.89 -2.8
913,500 + +0.5
913,631 + Rv0821c 0.11 +0.9
913,632 - Rv0821c 0.12 -0.0
913,632 - Rv0821c 0.12 -1.5
913,842 - Rv0821c 0.44 +0.2
914,135 - -0.1
914,186 + -0.1
914,186 + -1.6
914,205 - +0.5
914,211 + -0.3
914,212 - -0.2
914,338 + +0.0
914,339 - -0.2
914,622 + Rv0822c 0.18 +0.9
914,622 + Rv0822c 0.18 -0.1
914,622 + Rv0822c 0.18 +0.9
914,623 - Rv0822c 0.18 -0.3
914,829 + Rv0822c 0.28 +0.1
914,860 + Rv0822c 0.29 -0.3
914,861 - Rv0822c 0.29 -0.2
914,861 - Rv0822c 0.29 -0.1
914,862 + Rv0822c 0.29 -0.4
914,904 + Rv0822c 0.31 +0.1
914,904 + Rv0822c 0.31 -0.1
914,960 + Rv0822c 0.34 +1.3
914,960 + Rv0822c 0.34 -0.5
914,961 - Rv0822c 0.34 -0.4
914,961 - Rv0822c 0.34 +1.9
914,961 - Rv0822c 0.34 -0.8
915,125 + Rv0822c 0.42 -0.5
915,125 + Rv0822c 0.42 -0.3
915,125 + Rv0822c 0.42 -2.0
915,125 + Rv0822c 0.42 +0.3
915,126 - Rv0822c 0.42 -1.0
915,126 - Rv0822c 0.42 -1.3
915,126 - Rv0822c 0.42 -0.7
915,126 - Rv0822c 0.42 -1.8
915,126 - Rv0822c 0.42 +1.9
915,126 - Rv0822c 0.42 -2.4
915,126 - Rv0822c 0.42 +0.2
915,192 - Rv0822c 0.45 -0.0
915,192 - Rv0822c 0.45 +0.3
915,217 + Rv0822c 0.47 -0.2
915,217 + Rv0822c 0.47 +0.3
915,218 - Rv0822c 0.47 +0.2
915,323 - Rv0822c 0.52 -1.1
915,323 - Rv0822c 0.52 +2.1
915,330 + Rv0822c 0.52 -0.4
915,331 - Rv0822c 0.52 +0.6
915,331 - Rv0822c 0.52 +0.6
915,374 + Rv0822c 0.54 -0.3
915,425 + Rv0822c 0.57 +0.9
915,425 + Rv0822c 0.57 -0.3
915,426 - Rv0822c 0.57 +0.8
915,426 - Rv0822c 0.57 -0.3
915,426 - Rv0822c 0.57 -0.2
915,426 - Rv0822c 0.57 +0.7
915,426 - Rv0822c 0.57 +0.9
915,426 - Rv0822c 0.57 -0.2
915,429 + Rv0822c 0.57 -0.2
915,697 + Rv0822c 0.70 -0.9
915,697 + Rv0822c 0.70 -0.1
915,698 - Rv0822c 0.70 -0.1
915,947 + Rv0822c 0.82 -0.4
915,948 - Rv0822c 0.82 -1.2
915,948 - Rv0822c 0.82 -0.8
916,153 - +0.1
916,316 + +0.6
916,316 + -0.4
916,334 + +0.3
916,335 - +0.1
916,335 - -0.4
916,719 - Rv0823c 0.21 +0.1
916,876 + Rv0823c 0.34 +0.0
916,876 + Rv0823c 0.34 -0.1
916,964 + Rv0823c 0.42 -0.2
916,964 + Rv0823c 0.42 -0.2
916,964 + Rv0823c 0.42 -0.1
916,964 + Rv0823c 0.42 -1.2
916,965 - Rv0823c 0.42 -0.1
916,965 - Rv0823c 0.42 -0.6
916,965 - Rv0823c 0.42 -0.1
916,965 - Rv0823c 0.42 +0.3
916,965 - Rv0823c 0.42 -1.5
917,049 - Rv0823c 0.49 +0.1
917,049 - Rv0823c 0.49 +0.0
917,064 + Rv0823c 0.50 -0.2
917,177 - Rv0823c 0.60 +0.5
917,178 + Rv0823c 0.60 -1.1
917,179 - Rv0823c 0.60 -0.1
917,179 - Rv0823c 0.60 -0.1
917,228 - Rv0823c 0.64 +1.0

Or see this region's nucleotide sequence