Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0821c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0819 and Rv0820 are separated by 42 nucleotidesRv0820 and Rv0821c are separated by 55 nucleotidesRv0821c and Rv0822c are separated by 57 nucleotides Rv0819: Rv0819 - GCN5-related N-acetyltransferase, MshD, at 911,736 to 912,683 Rv0819 Rv0820: Rv0820 - Probable phosphate-transport ATP-binding protein ABC transporter PhoT, at 912,726 to 913,502 Rv0820 Rv0821c: Rv0821c - Probable phosphate-transport system transcriptional regulatory protein PhoY2, at 913,558 to 914,199 Rv0821c Rv0822c: Rv0822c - Conserved protein, at 914,257 to 916,311 Rv0822c Position (kb) 913 914 915Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2at 912.579 kb on + strand, within Rv0819at 912.580 kb on - strand, within Rv0819at 912.580 kb on - strand, within Rv0819at 912.640 kb on - strandat 912.678 kb on - strandat 912.723 kb on + strandat 912.723 kb on + strandat 912.724 kb on - strandat 912.763 kb on - strandat 912.765 kb on + strandat 912.766 kb on - strandat 912.942 kb on - strand, within Rv0820at 912.942 kb on - strand, within Rv0820at 912.945 kb on + strand, within Rv0820at 912.945 kb on + strand, within Rv0820at 912.945 kb on + strand, within Rv0820at 913.317 kb on + strand, within Rv0820at 913.317 kb on + strand, within Rv0820at 913.318 kb on - strand, within Rv0820at 913.340 kb on + strand, within Rv0820at 913.341 kb on - strand, within Rv0820at 913.420 kb on + strand, within Rv0820at 913.421 kb on - strand, within Rv0820at 913.500 kb on + strandat 913.631 kb on + strand, within Rv0821cat 913.632 kb on - strand, within Rv0821cat 913.632 kb on - strand, within Rv0821cat 913.842 kb on - strand, within Rv0821cat 914.135 kb on - strandat 914.186 kb on + strandat 914.186 kb on + strandat 914.205 kb on - strandat 914.211 kb on + strandat 914.212 kb on - strandat 914.338 kb on + strandat 914.339 kb on - strandat 914.622 kb on + strand, within Rv0822cat 914.622 kb on + strand, within Rv0822cat 914.622 kb on + strand, within Rv0822cat 914.623 kb on - strand, within Rv0822cat 914.829 kb on + strand, within Rv0822cat 914.860 kb on + strand, within Rv0822cat 914.861 kb on - strand, within Rv0822cat 914.861 kb on - strand, within Rv0822cat 914.862 kb on + strand, within Rv0822cat 914.904 kb on + strand, within Rv0822cat 914.904 kb on + strand, within Rv0822cat 914.960 kb on + strand, within Rv0822cat 914.960 kb on + strand, within Rv0822cat 914.961 kb on - strand, within Rv0822cat 914.961 kb on - strand, within Rv0822cat 914.961 kb on - strand, within Rv0822cat 915.125 kb on + strand, within Rv0822cat 915.125 kb on + strand, within Rv0822cat 915.125 kb on + strand, within Rv0822cat 915.125 kb on + strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.126 kb on - strand, within Rv0822cat 915.192 kb on - strand, within Rv0822cat 915.192 kb on - strand, within Rv0822c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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912,579 + Rv0819 0.89 -0.7
912,580 - Rv0819 0.89 -0.1
912,580 - Rv0819 0.89 -1.5
912,640 - -1.8
912,678 - -3.5
912,723 + -0.4
912,723 + -2.0
912,724 - -0.4
912,763 - -0.7
912,765 + -1.7
912,766 - -2.1
912,942 - Rv0820 0.28 -1.8
912,942 - Rv0820 0.28 -1.5
912,945 + Rv0820 0.28 -2.7
912,945 + Rv0820 0.28 +0.4
912,945 + Rv0820 0.28 -2.2
913,317 + Rv0820 0.76 -1.7
913,317 + Rv0820 0.76 -0.6
913,318 - Rv0820 0.76 -0.1
913,340 + Rv0820 0.79 -3.4
913,341 - Rv0820 0.79 -3.8
913,420 + Rv0820 0.89 -3.2
913,421 - Rv0820 0.89 -2.8
913,500 + +0.5
913,631 + Rv0821c 0.11 +0.9
913,632 - Rv0821c 0.12 -0.0
913,632 - Rv0821c 0.12 -1.5
913,842 - Rv0821c 0.44 +0.2
914,135 - -0.1
914,186 + -0.1
914,186 + -1.6
914,205 - +0.5
914,211 + -0.3
914,212 - -0.2
914,338 + +0.0
914,339 - -0.2
914,622 + Rv0822c 0.18 +0.9
914,622 + Rv0822c 0.18 -0.1
914,622 + Rv0822c 0.18 +0.9
914,623 - Rv0822c 0.18 -0.3
914,829 + Rv0822c 0.28 +0.1
914,860 + Rv0822c 0.29 -0.3
914,861 - Rv0822c 0.29 -0.2
914,861 - Rv0822c 0.29 -0.1
914,862 + Rv0822c 0.29 -0.4
914,904 + Rv0822c 0.31 +0.1
914,904 + Rv0822c 0.31 -0.1
914,960 + Rv0822c 0.34 +1.3
914,960 + Rv0822c 0.34 -0.5
914,961 - Rv0822c 0.34 -0.4
914,961 - Rv0822c 0.34 +1.9
914,961 - Rv0822c 0.34 -0.8
915,125 + Rv0822c 0.42 -0.5
915,125 + Rv0822c 0.42 -0.3
915,125 + Rv0822c 0.42 -2.0
915,125 + Rv0822c 0.42 +0.3
915,126 - Rv0822c 0.42 -1.0
915,126 - Rv0822c 0.42 -1.3
915,126 - Rv0822c 0.42 -0.7
915,126 - Rv0822c 0.42 -1.8
915,126 - Rv0822c 0.42 +1.9
915,126 - Rv0822c 0.42 -2.4
915,126 - Rv0822c 0.42 +0.2
915,192 - Rv0822c 0.45 -0.0
915,192 - Rv0822c 0.45 +0.3

Or see this region's nucleotide sequence