Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0766c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0764c and Rv0765c overlap by 1 nucleotidesRv0765c and Rv0766c overlap by 1 nucleotidesRv0766c and Rv0767c overlap by 4 nucleotidesRv0767c and Rv0768 are separated by 201 nucleotides Rv0764c: Rv0764c - Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM), at 856,682 to 858,037 Rv0764c Rv0765c: Rv0765c - Probable oxidoreductase, at 858,037 to 858,864 Rv0765c Rv0766c: Rv0766c - Probable cytochrome P450 123 Cyp123, at 858,864 to 860,072 Rv0766c Rv0767c: Rv0767c - Conserved hypothetical protein, at 860,069 to 860,710 Rv0767c Rv0768: Rv0768 - Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]), at 860,912 to 862,381 Rv0768 Position (kb) 858 859 860 861Strain fitness (log2 ratio) -1 0 1 2at 858.390 kb on - strand, within Rv0765cat 858.514 kb on + strand, within Rv0765cat 858.865 kb on + strandat 859.229 kb on - strand, within Rv0766cat 859.492 kb on + strand, within Rv0766cat 859.867 kb on - strand, within Rv0766cat 860.030 kb on - strandat 860.099 kb on - strandat 860.127 kb on + strandat 860.154 kb on + strand, within Rv0767cat 860.180 kb on + strand, within Rv0767cat 860.466 kb on + strand, within Rv0767cat 860.502 kb on + strand, within Rv0767cat 860.502 kb on + strand, within Rv0767cat 860.502 kb on + strand, within Rv0767cat 860.503 kb on - strand, within Rv0767cat 860.508 kb on + strand, within Rv0767cat 860.508 kb on + strand, within Rv0767cat 860.508 kb on + strand, within Rv0767cat 860.603 kb on + strand, within Rv0767cat 860.604 kb on - strand, within Rv0767cat 860.909 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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858,390 - Rv0765c 0.43 -0.1
858,514 + Rv0765c 0.58 -0.2
858,865 + -0.4
859,229 - Rv0766c 0.30 +0.8
859,492 + Rv0766c 0.52 +2.0
859,867 - Rv0766c 0.83 -0.0
860,030 - -0.4
860,099 - +0.3
860,127 + -0.1
860,154 + Rv0767c 0.13 +0.1
860,180 + Rv0767c 0.17 -1.1
860,466 + Rv0767c 0.62 +1.9
860,502 + Rv0767c 0.67 +1.0
860,502 + Rv0767c 0.67 +0.3
860,502 + Rv0767c 0.67 -0.3
860,503 - Rv0767c 0.68 +0.3
860,508 + Rv0767c 0.68 -0.3
860,508 + Rv0767c 0.68 -0.3
860,508 + Rv0767c 0.68 +0.0
860,603 + Rv0767c 0.83 +0.7
860,604 - Rv0767c 0.83 +0.3
860,909 + +0.6

Or see this region's nucleotide sequence