Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0661c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0658c and Rv0659c are separated by 275 nucleotidesRv0659c and Rv0660c overlap by 14 nucleotidesRv0660c and Rv0661c are separated by 109 nucleotidesRv0661c and Rv0662c overlap by 4 nucleotidesRv0662c and Rv0663 are separated by 113 nucleotides Rv0658c: Rv0658c - Probable conserved integral membrane protein, at 753,693 to 754,409 Rv0658c Rv0659c: Rv0659c - Toxin MazF2, at 754,685 to 754,993 Rv0659c Rv0660c: Rv0660c - Possible antitoxin MazE2, at 754,980 to 755,225 Rv0660c Rv0661c: Rv0661c - Possible toxin VapC7, at 755,335 to 755,772 Rv0661c Rv0662c: Rv0662c - Possible antitoxin VapB7, at 755,769 to 756,023 Rv0662c Rv0663: Rv0663 - Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase), at 756,137 to 758,500 Rv0663 Position (kb) 755 756Strain fitness (log2 ratio) -2 -1 0 1at 754.383 kb on + strandat 754.487 kb on + strandat 754.487 kb on + strandat 754.783 kb on + strand, within Rv0659cat 754.783 kb on + strand, within Rv0659cat 754.783 kb on + strand, within Rv0659cat 754.784 kb on - strand, within Rv0659cat 754.784 kb on - strand, within Rv0659cat 754.941 kb on - strand, within Rv0659cat 755.080 kb on + strand, within Rv0660cat 755.080 kb on + strand, within Rv0660cat 755.081 kb on - strand, within Rv0660cat 755.249 kb on + strandat 755.249 kb on + strandat 755.250 kb on - strandat 755.250 kb on - strandat 755.250 kb on - strandat 755.280 kb on - strandat 755.280 kb on - strandat 755.280 kb on - strandat 755.311 kb on + strandat 755.311 kb on + strandat 755.572 kb on - strand, within Rv0661cat 755.623 kb on + strand, within Rv0661cat 755.767 kb on + strandat 755.768 kb on - strandat 756.023 kb on + strandat 756.023 kb on + strandat 756.029 kb on + strandat 756.030 kb on - strandat 756.112 kb on + strandat 756.122 kb on + strandat 756.197 kb on + strandat 756.197 kb on + strandat 756.707 kb on + strand, within Rv0663

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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754,383 + +0.1
754,487 + -0.7
754,487 + -0.5
754,783 + Rv0659c 0.32 -0.1
754,783 + Rv0659c 0.32 +1.1
754,783 + Rv0659c 0.32 +0.2
754,784 - Rv0659c 0.32 -0.9
754,784 - Rv0659c 0.32 -0.4
754,941 - Rv0659c 0.83 -0.8
755,080 + Rv0660c 0.41 -0.2
755,080 + Rv0660c 0.41 -0.8
755,081 - Rv0660c 0.41 -0.2
755,249 + +0.2
755,249 + -0.2
755,250 - +0.5
755,250 - -1.8
755,250 - -1.4
755,280 - +0.6
755,280 - -0.5
755,280 - -0.3
755,311 + +0.5
755,311 + +0.9
755,572 - Rv0661c 0.54 -0.1
755,623 + Rv0661c 0.66 +1.5
755,767 + -0.0
755,768 - +0.2
756,023 + -0.7
756,023 + +0.3
756,029 + +0.1
756,030 - +0.9
756,112 + +0.6
756,122 + +0.5
756,197 + -0.1
756,197 + +0.2
756,707 + Rv0663 0.24 +0.0

Or see this region's nucleotide sequence