Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0370c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0368c and Rv0369c are separated by 5 nucleotidesRv0369c and Rv0370c are separated by 100 nucleotidesRv0370c and Rv0371c overlap by 4 nucleotidesRv0371c and Rv0372c overlap by 4 nucleotides Rv0368c: Rv0368c - Conserved hypothetical protein, at 445,314 to 446,525 Rv0368c Rv0369c: Rv0369c - Possible membrane oxidoreductase, at 446,531 to 447,046 Rv0369c Rv0370c: Rv0370c - Possible oxidoreductase, at 447,147 to 448,043 Rv0370c Rv0371c: Rv0371c - Conserved hypothetical protein, at 448,040 to 448,633 Rv0371c Rv0372c: Rv0372c - Conserved hypothetical protein, at 448,630 to 449,385 Rv0372c Position (kb) 447 448 449Strain fitness (log2 ratio) -2 -1 0 1 2 3at 446.147 kb on + strand, within Rv0368cat 446.147 kb on + strand, within Rv0368cat 446.148 kb on - strand, within Rv0368cat 446.148 kb on - strand, within Rv0368cat 446.283 kb on + strand, within Rv0368cat 446.284 kb on - strand, within Rv0368cat 446.284 kb on - strand, within Rv0368cat 446.332 kb on - strand, within Rv0368cat 446.366 kb on - strand, within Rv0368cat 447.006 kb on + strandat 447.074 kb on + strandat 447.601 kb on - strand, within Rv0370cat 447.735 kb on + strand, within Rv0370cat 447.784 kb on - strand, within Rv0370c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
remove
446,147 + Rv0368c 0.69 +0.4
446,147 + Rv0368c 0.69 -2.6
446,148 - Rv0368c 0.69 +0.4
446,148 - Rv0368c 0.69 -0.1
446,283 + Rv0368c 0.80 +1.9
446,284 - Rv0368c 0.80 -0.2
446,284 - Rv0368c 0.80 -0.2
446,332 - Rv0368c 0.84 -0.3
446,366 - Rv0368c 0.87 -0.3
447,006 + -0.1
447,074 + +3.7
447,601 - Rv0370c 0.51 -0.1
447,735 + Rv0370c 0.66 +0.4
447,784 - Rv0370c 0.71 +0.6

Or see this region's nucleotide sequence