Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0311

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0309 and Rv0310c are separated by 69 nucleotidesRv0310c and Rv0311 are separated by 23 nucleotidesRv0311 and Rv0312 are separated by 154 nucleotides Rv0309: Rv0309 - Possible conserved exported protein, at 377,931 to 378,587 Rv0309 Rv0310c: Rv0310c - Conserved protein, at 378,657 to 379,148 Rv0310c Rv0311: Rv0311 - Unknown protein, at 379,172 to 380,401 Rv0311 Rv0312: Rv0312 - Conserved hypothetical proline and threonine rich protein, at 380,556 to 382,418 Rv0312 Position (kb) 379 380 381Strain fitness (log2 ratio) -2 -1 0 1 2at 378.278 kb on + strand, within Rv0309at 379.004 kb on - strand, within Rv0310cat 379.075 kb on + strand, within Rv0310cat 379.081 kb on + strand, within Rv0310cat 379.187 kb on + strandat 379.279 kb on + strandat 379.280 kb on - strandat 379.280 kb on - strandat 379.349 kb on + strand, within Rv0311at 379.350 kb on - strand, within Rv0311at 379.544 kb on + strand, within Rv0311at 379.544 kb on + strand, within Rv0311at 380.076 kb on + strand, within Rv0311at 380.555 kb on + strandat 380.555 kb on + strandat 380.903 kb on - strand, within Rv0312

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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378,278 + Rv0309 0.53 -1.8
379,004 - Rv0310c 0.71 +0.3
379,075 + Rv0310c 0.85 +0.2
379,081 + Rv0310c 0.86 +0.3
379,187 + -0.3
379,279 + -0.2
379,280 - +0.2
379,280 - -0.4
379,349 + Rv0311 0.14 +0.4
379,350 - Rv0311 0.14 -0.4
379,544 + Rv0311 0.30 -0.4
379,544 + Rv0311 0.30 +1.9
380,076 + Rv0311 0.73 -0.0
380,555 + -0.6
380,555 + -0.8
380,903 - Rv0312 0.19 -0.5

Or see this region's nucleotide sequence