Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3775

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Rifampicin 0.00045 ug/mL
4,218,826	-				-0.3
4,218,861	+				+0.7
4,219,041	+		Rv3774	0.23	-0.0
4,219,054	+		Rv3774	0.25	+0.4
4,219,055	-		Rv3774	0.25	+1.6
4,219,055	-		Rv3774	0.25	-0.3
4,219,136	-		Rv3774	0.35	-0.2
4,219,136	-		Rv3774	0.35	-0.7
4,219,255	-		Rv3774	0.49	-0.4
4,219,297	+		Rv3774	0.54	+0.6
4,219,339	+		Rv3774	0.59	-0.9
4,219,340	-		Rv3774	0.60	+0.3
4,219,361	-		Rv3774	0.62	+2.0
4,219,435	-		Rv3774	0.71	+0.3
4,219,435	-		Rv3774	0.71	+0.2
4,219,435	-		Rv3774	0.71	-0.3
4,219,435	-		Rv3774	0.71	-0.2
4,219,512	+		Rv3774	0.80	-0.9
4,219,572	+		Rv3774	0.88	-1.9
4,219,572	+		Rv3774	0.88	+0.5
4,219,625	+				-0.1
4,219,626	-				-0.4
4,219,726	-				-0.1
4,219,825	+		Rv3775	0.11	-1.1
4,219,970	+		Rv3775	0.23	+0.3
4,220,004	+		Rv3775	0.26	+2.0
4,220,004	+		Rv3775	0.26	-0.4
4,220,005	-		Rv3775	0.26	-0.5
4,220,069	+		Rv3775	0.31	-0.1
4,220,069	+		Rv3775	0.31	+0.6
4,220,070	-		Rv3775	0.31	-0.1
4,220,183	+		Rv3775	0.40	+0.1
4,220,183	+		Rv3775	0.40	-1.8
4,220,183	+		Rv3775	0.40	+0.1
4,220,184	-		Rv3775	0.40	-0.3
4,220,184	-		Rv3775	0.40	-0.7
4,220,217	+		Rv3775	0.43	-1.2
4,220,217	+		Rv3775	0.43	-0.5
4,220,235	+		Rv3775	0.44	-0.4
4,220,235	+		Rv3775	0.44	-0.0
4,220,235	+		Rv3775	0.44	-0.5
4,220,236	-		Rv3775	0.44	-0.3
4,220,236	-		Rv3775	0.44	-1.7
4,220,236	-		Rv3775	0.44	-0.1
4,220,243	+		Rv3775	0.45	-0.3
4,220,243	+		Rv3775	0.45	-2.1
4,220,285	+		Rv3775	0.48	-0.5
4,220,491	+		Rv3775	0.65	-0.4
4,220,492	-		Rv3775	0.65	-0.3
4,220,492	-		Rv3775	0.65	-0.4
4,220,492	-		Rv3775	0.65	-0.0
4,220,492	-		Rv3775	0.65	-0.7
4,220,570	-		Rv3775	0.71	+0.3
4,220,613	+		Rv3775	0.74	-0.2
4,220,733	-		Rv3775	0.84	-0.3
4,220,733	-		Rv3775	0.84	-1.1
4,220,876	+				-0.5
4,220,911	-				+0.2
4,221,043	-				+0.7
4,221,089	-				-1.9
4,221,315	+		Rv3776	0.14	+1.2
4,221,325	+		Rv3776	0.15	+1.2
4,221,325	+		Rv3776	0.15	-0.7
4,221,325	+		Rv3776	0.15	-0.7
4,221,444	-		Rv3776	0.23	+2.1
4,221,567	-		Rv3776	0.31	+2.0
4,221,596	-		Rv3776	0.33	+3.0
4,221,700	+		Rv3776	0.39	-0.1
4,221,808	+		Rv3776	0.46	-0.1
4,221,808	+		Rv3776	0.46	+0.5
4,221,808	+		Rv3776	0.46	+0.2
4,221,808	+		Rv3776	0.46	-0.3
4,221,823	+		Rv3776	0.47	-0.6
4,221,906	+		Rv3776	0.52	-0.3
4,221,907	-		Rv3776	0.52	+0.1