Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3500c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Rifampicin 0.00045 ug/mL
3,918,227	+		Rv3499c	0.19	+1.0
3,918,227	+		Rv3499c	0.19	-0.6
3,918,227	+		Rv3499c	0.19	+0.2
3,918,228	-		Rv3499c	0.19	-2.7
3,918,228	-		Rv3499c	0.19	-0.4
3,918,276	+		Rv3499c	0.23	-0.1
3,918,435	-		Rv3499c	0.36	+0.5
3,918,441	+		Rv3499c	0.37	-1.6
3,918,442	-		Rv3499c	0.37	+0.4
3,918,445	-		Rv3499c	0.37	-0.0
3,918,463	+		Rv3499c	0.39	-0.8
3,918,464	-		Rv3499c	0.39	-0.4
3,918,563	+		Rv3499c	0.47	-1.3
3,918,563	+		Rv3499c	0.47	-1.0
3,918,563	+		Rv3499c	0.47	-0.9
3,918,614	-		Rv3499c	0.51	-1.3
3,918,746	-		Rv3499c	0.62	-0.1
3,919,017	-		Rv3499c	0.85	-0.3
3,919,017	-		Rv3499c	0.85	+0.3
3,919,101	+				-0.8
3,919,104	-				-0.2
3,919,255	-				+1.4
3,919,363	-		Rv3500c	0.17	-1.2
3,919,369	-		Rv3500c	0.18	-1.1
3,919,369	-		Rv3500c	0.18	-0.6
3,919,371	+		Rv3500c	0.18	-0.7
3,919,372	-		Rv3500c	0.18	+0.6
3,919,376	-		Rv3500c	0.19	-0.0
3,919,376	-		Rv3500c	0.19	-1.0
3,919,376	-		Rv3500c	0.19	+0.1
3,919,402	+		Rv3500c	0.22	-0.4
3,919,403	-		Rv3500c	0.22	+1.0
3,919,418	-		Rv3500c	0.23	-0.5
3,919,461	+		Rv3500c	0.29	+0.0
3,919,462	-		Rv3500c	0.29	-1.3
3,919,470	+		Rv3500c	0.30	-0.1
3,919,471	-		Rv3500c	0.30	-0.8
3,919,471	-		Rv3500c	0.30	+1.7
3,919,548	+		Rv3500c	0.39	+0.5
3,919,549	-		Rv3500c	0.39	-1.0
3,919,549	-		Rv3500c	0.39	-0.5
3,919,600	-		Rv3500c	0.45	+1.0
3,919,800	+		Rv3500c	0.69	+1.0
3,919,956	+		Rv3500c	0.87	-0.4
3,919,956	+		Rv3500c	0.87	+0.2
3,919,956	+		Rv3500c	0.87	-0.3
3,919,957	-		Rv3500c	0.87	-1.4
3,919,957	-		Rv3500c	0.87	+2.0
3,919,957	-		Rv3500c	0.87	-0.9
3,919,957	-		Rv3500c	0.87	+2.7
3,919,974	+		Rv3500c	0.89	-0.0
3,920,055	+				+2.0
3,920,056	-				-0.3
3,920,056	-				-0.2
3,920,121	+				-0.9
3,920,121	+				-0.5
3,920,121	+				-0.3
3,920,122	-				+2.0
3,920,122	-				-0.7
3,920,136	+				-1.1
3,920,136	+				-0.4
3,920,136	+				+0.6
3,920,137	-				-0.1
3,920,137	-				-1.0
3,920,289	+		Rv3501c	0.25	-0.7
3,920,290	-		Rv3501c	0.25	+1.7
3,920,290	-		Rv3501c	0.25	-0.5
3,920,330	+		Rv3501c	0.30	-1.0
3,920,331	-		Rv3501c	0.31	+2.0
3,920,718	+		Rv3501c	0.81	-0.5
3,921,030	-				+0.6