Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2947c

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2946c and Rv2947c overlap by 4 nucleotidesRv2947c and Rv2948c overlap by 4 nucleotides Rv2946c: Rv2946c - Probable polyketide synthase Pks1, at 3,291,503 to 3,296,353 Rv2946c Rv2947c: Rv2947c - Probable polyketide synthase Pks15, at 3,296,350 to 3,297,840 Rv2947c Rv2948c: Rv2948c - P-hydroxybenzoyl-AMP ligase FadD22, at 3,297,837 to 3,299,954 Rv2948c Position (kb) 3296 3297 3298Strain fitness (log2 ratio) -1 0 1 2at 3295.963 kb on + strandat 3295.963 kb on + strandat 3295.963 kb on + strandat 3296.050 kb on - strandat 3296.302 kb on + strandat 3296.303 kb on - strandat 3296.303 kb on - strandat 3296.425 kb on + strandat 3296.633 kb on + strand, within Rv2947cat 3296.733 kb on - strand, within Rv2947cat 3296.806 kb on + strand, within Rv2947cat 3296.806 kb on + strand, within Rv2947cat 3296.806 kb on + strand, within Rv2947cat 3296.807 kb on - strand, within Rv2947cat 3296.807 kb on - strand, within Rv2947cat 3296.807 kb on - strand, within Rv2947cat 3297.039 kb on + strand, within Rv2947cat 3297.039 kb on + strand, within Rv2947cat 3297.040 kb on - strand, within Rv2947cat 3297.040 kb on - strand, within Rv2947cat 3297.202 kb on - strand, within Rv2947cat 3297.235 kb on + strand, within Rv2947cat 3297.240 kb on - strand, within Rv2947cat 3297.240 kb on - strand, within Rv2947cat 3297.240 kb on - strand, within Rv2947cat 3297.240 kb on - strand, within Rv2947cat 3297.240 kb on - strand, within Rv2947cat 3297.288 kb on - strand, within Rv2947cat 3297.312 kb on + strand, within Rv2947cat 3297.313 kb on - strand, within Rv2947cat 3297.313 kb on - strand, within Rv2947cat 3297.344 kb on + strand, within Rv2947cat 3297.459 kb on + strand, within Rv2947cat 3297.460 kb on - strand, within Rv2947cat 3297.527 kb on + strand, within Rv2947cat 3297.560 kb on + strand, within Rv2947cat 3297.560 kb on + strand, within Rv2947cat 3297.561 kb on - strand, within Rv2947cat 3297.561 kb on - strand, within Rv2947cat 3297.561 kb on - strand, within Rv2947cat 3297.562 kb on + strand, within Rv2947cat 3297.562 kb on + strand, within Rv2947cat 3297.563 kb on - strand, within Rv2947cat 3297.720 kb on - strandat 3297.769 kb on + strandat 3297.769 kb on + strandat 3297.769 kb on + strandat 3297.769 kb on + strandat 3297.770 kb on - strandat 3297.770 kb on - strandat 3297.773 kb on + strandat 3297.774 kb on - strandat 3297.835 kb on + strandat 3297.835 kb on + strandat 3297.836 kb on - strandat 3298.115 kb on - strand, within Rv2948cat 3298.142 kb on - strand, within Rv2948cat 3298.281 kb on + strand, within Rv2948cat 3298.281 kb on + strand, within Rv2948cat 3298.281 kb on + strand, within Rv2948cat 3298.281 kb on + strand, within Rv2948cat 3298.281 kb on + strand, within Rv2948cat 3298.281 kb on + strand, within Rv2948cat 3298.282 kb on - strand, within Rv2948cat 3298.282 kb on - strand, within Rv2948cat 3298.282 kb on - strand, within Rv2948cat 3298.305 kb on + strand, within Rv2948cat 3298.808 kb on - strand, within Rv2948cat 3298.808 kb on - strand, within Rv2948cat 3298.811 kb on + strand, within Rv2948cat 3298.811 kb on + strand, within Rv2948cat 3298.812 kb on - strand, within Rv2948cat 3298.812 kb on - strand, within Rv2948cat 3298.832 kb on + strand, within Rv2948c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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3,295,963 + -0.8
3,295,963 + +0.6
3,295,963 + +0.2
3,296,050 - -1.2
3,296,302 + +0.3
3,296,303 - -0.6
3,296,303 - -0.4
3,296,425 + +0.5
3,296,633 + Rv2947c 0.19 -0.2
3,296,733 - Rv2947c 0.26 -0.4
3,296,806 + Rv2947c 0.31 -0.1
3,296,806 + Rv2947c 0.31 -0.7
3,296,806 + Rv2947c 0.31 -1.0
3,296,807 - Rv2947c 0.31 -0.9
3,296,807 - Rv2947c 0.31 -0.4
3,296,807 - Rv2947c 0.31 -0.4
3,297,039 + Rv2947c 0.46 -1.2
3,297,039 + Rv2947c 0.46 +0.1
3,297,040 - Rv2947c 0.46 -0.2
3,297,040 - Rv2947c 0.46 -1.6
3,297,202 - Rv2947c 0.57 -0.5
3,297,235 + Rv2947c 0.59 +1.0
3,297,240 - Rv2947c 0.60 -1.3
3,297,240 - Rv2947c 0.60 -0.4
3,297,240 - Rv2947c 0.60 -0.2
3,297,240 - Rv2947c 0.60 +0.4
3,297,240 - Rv2947c 0.60 -0.5
3,297,288 - Rv2947c 0.63 -0.4
3,297,312 + Rv2947c 0.65 +0.1
3,297,313 - Rv2947c 0.65 -0.3
3,297,313 - Rv2947c 0.65 -0.2
3,297,344 + Rv2947c 0.67 -0.4
3,297,459 + Rv2947c 0.74 +0.4
3,297,460 - Rv2947c 0.74 -0.0
3,297,527 + Rv2947c 0.79 -0.9
3,297,560 + Rv2947c 0.81 -0.2
3,297,560 + Rv2947c 0.81 -0.1
3,297,561 - Rv2947c 0.81 +1.0
3,297,561 - Rv2947c 0.81 -0.4
3,297,561 - Rv2947c 0.81 -0.4
3,297,562 + Rv2947c 0.81 -0.2
3,297,562 + Rv2947c 0.81 +0.7
3,297,563 - Rv2947c 0.81 +2.0
3,297,720 - -0.4
3,297,769 + +1.6
3,297,769 + -0.3
3,297,769 + -1.0
3,297,769 + -0.3
3,297,770 - -0.2
3,297,770 - -0.1
3,297,773 + -0.1
3,297,774 - +1.0
3,297,835 + -0.3
3,297,835 + -0.2
3,297,836 - +0.3
3,298,115 - Rv2948c 0.13 -0.4
3,298,142 - Rv2948c 0.14 +0.2
3,298,281 + Rv2948c 0.21 -0.1
3,298,281 + Rv2948c 0.21 +0.0
3,298,281 + Rv2948c 0.21 -1.5
3,298,281 + Rv2948c 0.21 -0.2
3,298,281 + Rv2948c 0.21 -1.3
3,298,281 + Rv2948c 0.21 +1.1
3,298,282 - Rv2948c 0.21 +1.0
3,298,282 - Rv2948c 0.21 +0.4
3,298,282 - Rv2948c 0.21 -0.3
3,298,305 + Rv2948c 0.22 -0.3
3,298,808 - Rv2948c 0.46 -0.2
3,298,808 - Rv2948c 0.46 +0.5
3,298,811 + Rv2948c 0.46 -1.6
3,298,811 + Rv2948c 0.46 -0.1
3,298,812 - Rv2948c 0.46 -1.1
3,298,812 - Rv2948c 0.46 -0.2
3,298,832 + Rv2948c 0.47 -1.2

Or see this region's nucleotide sequence