Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2941

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Rifampicin 0.00045 ug/mL
3,282,467	-				+0.9
3,282,561	+				+0.8
3,282,561	+				+0.8
3,282,561	+				+0.7
3,282,561	+				+1.2
3,282,562	-				+0.5
3,282,562	-				-0.1
3,282,562	-				+0.7
3,282,564	+				+1.2
3,282,564	+				+0.5
3,282,715	+				+0.9
3,282,715	+				+0.8
3,282,715	+				+0.8
3,282,816	+				+1.2
3,282,816	+				+2.0
3,282,816	+				+0.8
3,282,817	-				+0.3
3,282,817	-				-0.2
3,282,817	-				+0.1
3,282,817	-				+2.2
3,282,817	-				+1.2
3,282,817	-				-0.5
3,282,820	+				+0.8
3,282,821	-				+0.0
3,282,861	+				+1.1
3,282,861	+				+1.3
3,282,862	-				+1.0
3,282,862	-				-1.3
3,282,862	-				-0.6
3,282,898	+				+0.3
3,282,899	-				+0.2
3,282,901	+				+0.8
3,282,901	+				+1.0
3,283,053	-				-1.0
3,283,089	+				+0.3
3,283,089	+				-0.1
3,283,090	-				+0.4
3,283,409	+				+0.4
3,283,410	-				+1.0
3,283,416	+				+0.2
3,283,445	-				+0.8
3,283,467	+				+0.9
3,283,468	-				+0.7
3,283,557	+		Rv2941	0.13	+0.9
3,283,557	+		Rv2941	0.13	+0.9
3,283,558	-		Rv2941	0.13	+0.3
3,283,654	+		Rv2941	0.18	+0.3
3,283,688	+		Rv2941	0.20	+0.7
3,283,689	-		Rv2941	0.20	+2.4
3,283,689	-		Rv2941	0.20	+1.0
3,283,689	-		Rv2941	0.20	+0.6
3,283,689	-		Rv2941	0.20	+0.2
3,283,689	-		Rv2941	0.20	+1.1
3,283,797	+		Rv2941	0.27	+0.7
3,283,975	+		Rv2941	0.37	+0.8
3,284,212	+		Rv2941	0.50	+0.9
3,284,212	+		Rv2941	0.50	+0.7
3,284,213	-		Rv2941	0.50	+0.7
3,284,213	-		Rv2941	0.50	+0.4
3,284,213	-		Rv2941	0.50	+0.6
3,284,213	-		Rv2941	0.50	+0.7
3,284,213	-		Rv2941	0.50	+1.1
3,284,213	-		Rv2941	0.50	+0.6
3,284,213	-		Rv2941	0.50	+0.8
3,284,344	-		Rv2941	0.58	+0.6
3,284,344	-		Rv2941	0.58	+1.3
3,284,344	-		Rv2941	0.58	+0.2
3,284,393	+		Rv2941	0.61	+0.5
3,284,444	+		Rv2941	0.64	+1.5
3,284,460	+		Rv2941	0.65	+0.5
3,284,460	+		Rv2941	0.65	+1.2
3,284,460	+		Rv2941	0.65	+0.7
3,284,460	+		Rv2941	0.65	+0.5
3,284,461	-		Rv2941	0.65	+1.1
3,284,461	-		Rv2941	0.65	+1.7
3,284,999	+				+1.0
3,285,076	-				-1.5
3,285,093	-				-1.4
3,285,106	+				-2.4
3,285,107	-				-1.2
3,285,109	-				-0.7
3,285,109	-				-1.7
3,285,369	+		Rv2942	0.11	+3.0
3,285,369	+		Rv2942	0.11	-1.2
3,285,424	+		Rv2942	0.13	-0.9
3,285,427	+		Rv2942	0.13	-2.0
3,285,427	+		Rv2942	0.13	-1.6
3,285,427	+		Rv2942	0.13	+3.0
3,285,427	+		Rv2942	0.13	-1.4
3,285,428	-		Rv2942	0.13	-0.3
3,285,428	-		Rv2942	0.13	-1.8
3,285,428	-		Rv2942	0.13	-1.3
3,285,428	-		Rv2942	0.13	+0.1
3,285,428	-		Rv2942	0.13	-1.2
3,285,699	-		Rv2942	0.23	-0.9
3,285,752	+		Rv2942	0.25	+0.6
3,285,753	-		Rv2942	0.25	-0.9
3,285,988	+		Rv2942	0.33	-1.2
3,286,038	-		Rv2942	0.35	+0.2