Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1641

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1640c and Rv1641 are separated by 237 nucleotidesRv1641 and Rv1642 are separated by 49 nucleotidesRv1642 and Rv1643 are separated by 61 nucleotidesRv1643 and Rv1644 are separated by 32 nucleotides Rv1640c: Rv1640c - Lysyl-tRNA synthetase 2 LysX, at 1,848,517 to 1,852,035 Rv1640c Rv1641: Rv1641 - Probable initiation factor if-3 InfC, at 1,852,273 to 1,852,878 Rv1641 Rv1642: Rv1642 - 50S ribosomal protein L35 RpmI, at 1,852,928 to 1,853,122 Rv1642 Rv1643: Rv1643 - 50S ribosomal protein L20 RplT, at 1,853,184 to 1,853,573 Rv1643 Rv1644: Rv1644 - Possible 23S rRNA methyltransferase TsnR, at 1,853,606 to 1,854,388 Rv1644 Position (kb) 1852 1853Strain fitness (log2 ratio) -2 -1 0 1at 1851.300 kb on - strand, within Rv1640cat 1851.322 kb on + strand, within Rv1640cat 1851.574 kb on - strand, within Rv1640cat 1851.684 kb on - strandat 1851.749 kb on - strandat 1851.866 kb on - strandat 1851.907 kb on + strandat 1851.908 kb on - strandat 1851.958 kb on - strandat 1851.979 kb on - strandat 1852.876 kb on + strandat 1853.173 kb on + strandat 1853.173 kb on + strandat 1853.662 kb on - strandat 1853.662 kb on - strandat 1853.662 kb on - strandat 1853.745 kb on + strand, within Rv1644at 1853.745 kb on + strand, within Rv1644at 1853.746 kb on - strand, within Rv1644at 1853.848 kb on + strand, within Rv1644at 1853.849 kb on - strand, within Rv1644

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
remove
1,851,300 - Rv1640c 0.79 -0.1
1,851,322 + Rv1640c 0.80 -1.2
1,851,574 - Rv1640c 0.87 -1.6
1,851,684 - -1.8
1,851,749 - -0.4
1,851,866 - +0.4
1,851,907 + -0.1
1,851,908 - -0.5
1,851,958 - +0.1
1,851,979 - +0.8
1,852,876 + -1.9
1,853,173 + -1.9
1,853,173 + -0.2
1,853,662 - +0.1
1,853,662 - -0.9
1,853,662 - -0.8
1,853,745 + Rv1644 0.18 -0.3
1,853,745 + Rv1644 0.18 +0.6
1,853,746 - Rv1644 0.18 +0.2
1,853,848 + Rv1644 0.31 +0.0
1,853,849 - Rv1644 0.31 +1.6

Or see this region's nucleotide sequence